China Factory Direct
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| CAS number | 114772-53-1 |
| Product name | 4'-Methyl-2-cyanobiphenyl |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeElectronic GradeMaterial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Insecticidal intermediate for synthesizing pyrethroid compounds (e.g., structural modification of lambda-cyhalothrin) | Undergoes nucleophilic substitution with haloalkanes, or multi-step synthesis—including reduction and acylation—to produce active ingredients |
| Pharmaceuticals | Synthetic intermediate for anti-inflammatory drugs and selective COX-2 inhibitors | Participates in Suzuki coupling, cyanide hydrolysis/reduction, and other reactions to construct biphenyl scaffolds and nitrogen-containing functional groups |
| Liquid Crystal Materials | Key structural unit in high-performance nematic liquid crystal monomers, enhancing clearing point and dielectric anisotropy | Modulates molecular polarizability through synergistic polarity of cyano and methyl groups; side chains are introduced via palladium-catalyzed cross-coupling |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Using a reversed-phase C18 chromatographic column, with methanol-water or acetonitrile-water as the mobile phase, and a UV detector (e.g., 254 nm) for detection. Quantification of the main component is performed using external standard or internal standard methods. |
| Purity Analysis | Gas Chromatography-Mass Spectrometry (GC-MS) | After dissolving the sample in an appropriate solvent, the components are separated by gas chromatography and identified qualitatively by mass spectrometry to assess the purity of the compound. Suitable for samples with good volatility. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Use of ¹H-NMR and ¹³C-NMR to analyze the structure of the compound and confirm the chemical environment of hydrogen and carbon atoms consistent with the target structure. |
| Residual Solvent Detection | Gas Chromatography (GC) | According to pharmacopoeias or relevant standards (e.g., ICH Q3C), headspace sampling combined with gas chromatography is used to detect residual organic solvents (e.g., methanol, ethanol, acetone) from the production process. |
| Moisture Content | Karl Fischer Titration | Utilizes electrochemical titration principles to determine moisture content in the sample, divided into volumetric and coulometric methods, suitable for trace moisture detection. |
| Melting Point Determination | Melting Point Apparatus Method | Uses automatic or semi-automatic melting point apparatus to measure the initial and final melting temperatures of the sample, assessing its physical properties against the standard. |
| Related Substances (Impurities) Analysis | High-Performance Liquid Chromatography (HPLC) | Optimize chromatographic conditions to separate the main peak from impurity peaks, using gradient elution to detect and quantify each related substance, evaluating the impurity profile of the sample. |
| Crystal Form Analysis | X-ray Diffraction (XRD) | Analyzes the crystal structure of solid samples, used to identify different crystal forms and ensure consistency between batches (if polymorphism exists). |
| Particle Size Distribution | Laser Particle Size Analysis | Applicable to solid active pharmaceutical ingredients, measures particle size distribution through laser scattering principles, affecting solubility and formulation performance. |
| UV Absorption Characteristics | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Scans in a specified wavelength range (e.g., 200–400 nm) to determine the maximum absorption wavelength (λmax), used for qualitative or auxiliary quantitative analysis. |
| Test Item | Specification |
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| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 128–132°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.