N-Benzyloxycarbonyl-L-proline Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1148-11-4 |
| Product name | N-Benzyloxycarbonyl-L-proline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-Benzyloxycarbonyl-L-proline
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-Benzyloxycarbonyl-L-proline Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-Benzyloxycarbonyl-L-proline
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral drug synthesis intermediate for constructing proline derivatives or peptide compounds (e.g., angiotensin-converting enzyme inhibitors) | Used as an amino acid-protected monomer to introduce Cbz-protected proline via condensation reactions in solid-phase or solution-phase peptide synthesis |
| Biochemistry | Protected amino acid reagent for peptide and protein research, enabling selective reaction site control | Applied in mild basic conditions for Cbz deprotection (e.g., hydrogenolysis) prior to subsequent chain elongation or modification |
| Research Reagents | Organic synthesis intermediate for preparing chiral catalysts or functionalized proline analogues | Employed as a starting material in esterification, amidation, or cyclization reactions to construct complex chiral molecular frameworks |
| Cosmetics | Potential precursor to peptide-based active ingredients (e.g., antioxidant or anti-aging peptides) | Integrated into final products only after multi-step synthesis and purification; limited practical application |
Manufacturing Quality Control of N-Benzyloxycarbonyl-L-proline
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 210 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and detection of impurities by reversed-phase HPLC with UV detection; identification and quantification based on relative retention times and response factors. |
| Residual Solvents | GC-FID | Identification and quantification of residual organic solvents using gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to determine water content based on stoichiometric reaction with water. |
| Heavy Metals | ICP-OES | Multi-element quantification of heavy metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma optical emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 600-700 C followed by sulfuric acid treatment and weighing of residual inorganic ash. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid transitions to liquid, indicating purity and identity. |
| Loss on Drying | Thermogravimetric Analysis | Measurement of mass loss upon heating under controlled conditions to quantify volatile components and moisture. |
| Residual Palladium | ICP-MS | Ultra-trace quantification of palladium residue (from catalytic hydrogenation steps) using inductively coupled plasma mass spectrometry. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms by filtration, membrane transfer to culture media, and colony counting after incubation. |
Technical Specifications of N-Benzyloxycarbonyl-L-proline
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 78.0 to 82.0 °C |
| Optical Rotation | -42.0 to -38.0 ° (c=1, in DMF) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-Benzyloxycarbonyl-L-proline
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-Benzyloxycarbonyl-L-proline
Packaging of N-Benzyloxycarbonyl-L-proline
Industrial N-Benzyloxycarbonyl-L-proline Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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