China Factory Direct
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| CAS number | 114873-00-6 |
| Product name | BOC-L-2-Fluorophe |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Synthesis of fluorinated peptides and protein analogs | Used as a chiral building block in solid-phase or solution-phase peptide synthesis to incorporate fluorophenylalanine residues, thereby modulating metabolic stability and biological activity of drug candidates |
| Biochemical Research | Investigation of protein structure–function relationships | Labeled onto target proteins to enable conformational dynamics analysis via 19F NMR spectroscopy |
| New Drug Development | Development of anticancer and antiviral candidate compounds | Employed as an intermediate in targeted drug molecule design to enhance membrane permeability and target selectivity |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 210-220 nm. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess determination using a chiral stationary phase with UV detection, resolving L- and D-enantiomers. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the reaction of iodine with water in a pyridine-methanol solvent system. |
| Residual Solvents | GC-FID | Separation and quantification of volatile organic solvents (e.g., DMF, THF, ethyl acetate) using capillary GC with flame ionization detection. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Hg, Ni) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 500-600 C followed by weighing of residual inorganic ash after sulfuric acid treatment. |
| Optical Rotation | [alpha]D Measurement | Determination of specific rotation using a polarimeter at 20 C with sodium D-line (589 nm) in specified solvent (e.g., 1M HCl). |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., BOC-deprotected form, diastereomers) using gradient reversed-phase HPLC. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample via light scattering pattern to determine D10, D50, D90 values. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic mesophilic bacteria and molds/yeasts by filtration, membrane transfer to selective agar media, and incubation. |
| pH of Solution | Potentiometric Titration | Measurement of hydrogen ion activity in aqueous suspension (1% w/v) using calibrated glass electrode and pH meter. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 142-146°C |
| Optical Rotation | +9±1° (c=1, in 1M HCl) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.