BOC-L-2-Chlorophe Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 114873-02-8 |
| Product name | BOC-L-2-Chlorophe |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for BOC-L-2-Chlorophe
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk BOC-L-2-Chlorophe Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of BOC-L-2-Chlorophe
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in synthesizing chlorinated phenyl-containing peptide drugs, such as targeted protein degraders (PROTACs) and G protein-coupled receptor (GPCR) modulators | Employed as a chiral building block in solid-phase peptide synthesis (SPPS), incorporated into the peptide chain via Fmoc/BOC orthogonal protection strategies; functional groups are subsequently introduced via palladium-catalyzed cross-coupling or nucleophilic substitution |
| Organic Synthesis | Key precursor to chiral chloro-phenylalanine derivatives for constructing asymmetric C–Cl bonds and aryl ring functionalization | After enzymatic resolution with L-selective enzymes or chiral catalytic hydrogenation to obtain optically pure material, used in transition metal-catalyzed C–C bond coupling reactions, including Suzuki and Heck couplings |
| Agrochemical R&D | Structural motif for novel chiral herbicides and plant growth regulators | Integrated into molecular docking-based optimization design; the 2-chlorophenyl group enhances lipophilicity and target binding affinity, followed by derivatization (e.g., amidation, esterification) and structure–activity relationship (SAR) screening |
Manufacturing Quality Control of BOC-L-2-Chlorophe
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification based on peak area comparison with reference standard using reversed-phase chromatography and UV detection at 210-230 nm. |
| Chiral Purity | Chiral HPLC | Enantiomeric separation on a chiral stationary phase with UV detection; ratio of L-isomer to total isomers calculated. |
| Water Content | Karl Fischer Titration | Electrochemical titration where iodine reacts stoichiometrically with water in anhydrous methanol/pyridine medium. |
| Residual Solvents | GC-FID | Separation and quantification of volatile organic solvents (e.g., DMF, THF, ethyl acetate) using capillary GC with flame ionization detection. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification after acid digestion, based on mass-to-charge ratio detection in plasma ionization. |
| Chloride Impurity | Ion Chromatography | Separation of chloride anions on an anion-exchange column with suppressed conductivity detection. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., BOC-deprotected, racemized, or hydrolyzed forms) using gradient RP-HPLC. |
| Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution at specified concentration and wavelength. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid transitions to liquid, indicating crystallinity and purity. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of particulates or discoloration against established reference standards. |
| Residue on Ignition | Gravimetric Analysis | Mass of inorganic residue remaining after high-temperature ashing of sample, indicating non-volatile inorganic impurities. |
| pH of Solution | Potentiometric pH Measurement | Determination of hydrogen ion activity in aqueous suspension using calibrated glass electrode and reference electrode. |
Technical Specifications of BOC-L-2-Chlorophe
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Optical Rotation | -24.5±1.0° (c=1, in 1M HCl) |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of BOC-L-2-Chlorophe
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of BOC-L-2-Chlorophe
Packaging of BOC-L-2-Chlorophe
Industrial BOC-L-2-Chlorophe Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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