China Factory Direct
|
|
| CAS number | 114873-03-9 |
| Product name | (S)-N-BOC-3-Chlorophenylalanine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Key intermediate for synthesizing peptide-based drugs, used to incorporate chlorophenylalanine structural units | Participates in amide bond formation following deprotection (e.g., TFA treatment) in solid-phase or solution-phase peptide synthesis |
| Biochemistry | Preparation of modified peptides containing non-natural amino acids to study protein structure–function relationships | Selective coupling and deprotection under Fmoc/t-Boc strategies to assemble target peptide chains |
| Organic Synthesis | Chiral building block for synthesizing complex, biologically active molecules | Introduced into specific structures via palladium-catalyzed coupling, reduction, or other functional group transformations |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 210-220 nm. |
| Chiral Purity | Chiral HPLC | Separation of enantiomers on a chiral stationary phase; L-isomer content determined by relative peak area. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of iodine with water in pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of trace metal impurities (e.g., Pb, Cd, Ni, Fe) after acid digestion. |
| Chloride Ion | Ion Chromatography | Separation and quantification of chloride anion using suppressed conductivity detection. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residue after microwave-assisted acid digestion. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of visible particulates or foreign matter under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light at specified wavelength and concentration to confirm chiral integrity. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., deprotected, hydrolyzed, or diastereomeric forms) using gradient elution. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after high-temperature ashing at 750-800 C. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 142~146°C |
| Optical Rotation | +13.0 to +16.0° (c=1, in 1M HCl) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.