China Factory Direct
|
|
| CAS number | 114873-11-9 |
| Product name | BOC-D-3-Fluorophe |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a chiral building block for constructing fluorinated peptide-based drug molecules | Introduced as the D-configured 3-fluorophenylalanine residue in solid-phase or solution-phase peptide synthesis |
| Medicinal Chemistry | Employed in the design and synthesis of protease inhibitors or receptor ligands | Incorporated into target molecule construction via amide bond formation or other functional group linkages |
| Biochemical Research | Applied as a non-canonical amino acid probe to investigate protein structure–function relationships | Site-specifically incorporated into proteins or peptide chains for analysis using fluorescence or NMR techniques |
| Organic Synthesis | Utilized as a fluorinated chiral intermediate in asymmetric synthesis reactions | Participates in coupling, condensation, and other transformations following deprotection (e.g., BOC removal with TFA) |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification via reverse-phase HPLC with UV detection at 210-220 nm, using a calibrated standard curve. |
| Chiral Purity | Chiral HPLC | Enantiomeric separation on a chiral stationary phase with UV detection to determine D-isomer excess. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generated in situ to quantify water based on stoichiometric reaction. |
| Residual Solvents | GC-FID | Headspace or direct injection GC with flame ionization detection, quantifying solvents against reference standards. |
| Heavy Metals | ICP-MS | Multi-element detection of trace metals after acid digestion, using isotopic mass spectrometry for high sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride anions using suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Ignition at 700-800 C followed by weighing of non-volatile inorganic residue. |
| Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution to confirm chiral integrity. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to determine size distribution of solid particles in suspension. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities using gradient reverse-phase HPLC with UV detection. |
| pH (1% w/v aqueous solution) | Potentiometric pH Measurement | Determination of hydrogen ion activity using calibrated glass electrode in aqueous suspension. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms via filtration, membrane transfer to agar media, and colony counting. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -7.0±1.0° (c=1, in 1M HCl) |
| Melting Point | 148–152°C |
| Identification (NMR) | Conforms to reference spectrum |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.