N-Carbobenzyloxy-L-valine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1149-26-4 |
| Product name | N-Carbobenzyloxy-L-valine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-Carbobenzyloxy-L-valine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-Carbobenzyloxy-L-valine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-Carbobenzyloxy-L-valine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing peptide-based drugs, including angiotensin-converting enzyme (ACE) inhibitors, antiviral agents, and anticancer peptides | Used as an N-α-protected amino acid in solid-phase or solution-phase peptide synthesis to extend peptide chains; the CBZ protecting group is removed under hydrogenation or acidic conditions prior to subsequent coupling reactions |
| Biochemical Research | Synthesis of peptide segments for protein structure and function studies, as well as construction of enzyme substrates or inhibitors | Peptide synthesis at laboratory scale using standard Fmoc/t-Boc or CBZ protection strategies, typically combined with coupling reagents such as DCC and HOBt |
| Agricultural Chemicals | Synthetic precursor for certain peptidomimetic agrochemicals, such as plant growth regulators or insecticides | Incorporated into specific bioactive molecular scaffolds via multi-step organic synthesis, followed by functional group modification and structural optimization |
| Cosmetics | Development of bioactive peptides with signaling or repair functions (e.g., anti-aging peptides) | Fragment condensation under mild conditions to prevent racemization at chiral centers; high-purity peptides are obtained through purification for formulation use |
Manufacturing Quality Control of N-Carbobenzyloxy-L-valine
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of the sample and compare it with reference spectra to confirm consistency of characteristic functional groups in the molecular structure (e.g., amide bonds, benzene rings, carboxyl groups). |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Use NMR technology to analyze chemical shifts, coupling constants, and integration areas of hydrogen atoms in the compound to verify structural characteristics of CBZ-L-valine. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Employ a reversed-phase C18 column with an appropriate mobile phase (e.g., acetonitrile-water or methanol-phosphate buffer) under isocratic or gradient elution. Quantify the active ingredient using a UV detector (typically 210–254 nm). |
| Related Substances (Impurity Profiling) | High-Performance Liquid Chromatography (HPLC) | Similar conditions as assay, but optimized for separation and detection of potential impurities (e.g., unreacted starting materials, by-products, degradation products). Quantification is usually performed using area normalization or main component self-dilution method with correction factors. |
| Specific Optical Rotation | Polarimetry | Measure the optical rotation of a solution at specified temperature (usually 20°C or 25°C) and wavelength (sodium D line, 589.3 nm), then calculate the specific rotation to assess L-configuration purity and detect potential optical isomer impurities. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant Weight Drying at Atmospheric Pressure | Dry the sample at 105°C until constant weight and determine the percentage weight loss to evaluate moisture and volatile content. |
| Sulfated Ash | High-Temperature Incineration Method | After charring the sample, incinerate it in a high-temperature furnace at 700–800°C until constant weight. Measure the inorganic residue (ash) to control levels of inorganic impurities. |
| Water Content | Karl Fischer Titration | Use volumetric or coulometric Karl Fischer titration for specific determination of water content; suitable for thermally unstable samples or those containing crystalline water. |
| pH Value | pH Meter Method | Prepare an aqueous solution of defined concentration (e.g., 1% w/v) and measure its acidity or alkalinity using a calibrated pH meter to reflect the state of free carboxyl/amino groups and possible acidic or basic impurities. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection GC with FID detection to test for residual organic solvents (e.g., dichloromethane, methanol, ethanol) from synthesis or purification processes, according to ICH Q3C guidelines. |
Technical Specifications of N-Carbobenzyloxy-L-valine
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 72-76°C |
| Optical Rotation | -3.5 to -5.0° (c=1, in 1M HCl) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-Carbobenzyloxy-L-valine
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| Lot/Batch Number | *Required fields | |
NMR Spectra of N-Carbobenzyloxy-L-valine
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Industrial N-Carbobenzyloxy-L-valine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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