ethyl 3-oxo-4-(2,4,5-trifluorophenyl)butanoate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1151240-88-8 |
| Product name | ethyl 3-oxo-4-(2,4,5-trifluorophenyl)butanoate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for ethyl 3-oxo-4-(2,4,5-trifluorophenyl)butanoate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk ethyl 3-oxo-4-(2,4,5-trifluorophenyl)butanoate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of ethyl 3-oxo-4-(2,4,5-trifluorophenyl)butanoate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Key pharmaceutical intermediate | Used in the synthesis of dipeptidyl peptidase-4 (DPP-4) inhibitors (e.g., teneligliptin), where it contributes the pyrrolidinone structural motif to the drug molecule’s core scaffold. |
| Organic Synthesis | Chiral building block | Applied in asymmetric reduction, chiral resolution, or cyclization reactions as a specifically functionalized β-keto ester compound for preparing active pharmaceutical ingredients (APIs) with defined stereochemistry. |
Manufacturing Quality Control of ethyl 3-oxo-4-(2,4,5-trifluorophenyl)butanoate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210-230 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities using gradient HPLC-UV; identification by retention time matching and/or spiked standards. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., ethanol, ethyl acetate) by headspace GC with flame ionization detection using calibrated external standards. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni, As) after acid digestion using inductively coupled plasma mass spectrometry with isotope dilution calibration. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after controlled ashing at 600-750 C and weighing of the cooled crucible. |
| Optical Rotation | Polarimetry | Determines specific optical rotation using sodium D-line light to assess chiral purity and enantiomeric excess. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid using calibrated capillary tube method per USP <741>. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determines acidity/basicity of a saturated aqueous suspension using calibrated glass electrode and pH meter. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity against established reference standards under controlled white-light conditions. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution in dry powder form using Mie scattering theory and calibrated laser diffraction instrument. |
Technical Specifications of ethyl 3-oxo-4-(2,4,5-trifluorophenyl)butanoate
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Refractive Index (n20/D) | 1.495–1.505 |
| Relative Density (20°C/25°C) | 1.22–1.26 g/cm³ |
| Odor | Characteristic mild ester odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of ethyl 3-oxo-4-(2,4,5-trifluorophenyl)butanoate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of ethyl 3-oxo-4-(2,4,5-trifluorophenyl)butanoate
Industrial ethyl 3-oxo-4-(2,4,5-trifluorophenyl)butanoate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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