China Factory Direct
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| CAS number | 115186-31-7 |
| Product name | N-Boc-N'-Fmoc-D-lysine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Biopharmaceutical R&D | Peptide synthesis intermediate | Used as a protected amino acid monomer in solid-phase or solution-phase peptide synthesis to incorporate D-lysine residues; Boc and Fmoc groups provide orthogonal protection of the α-amino group, enabling selective deprotection and coupling |
| Chemical reagent manufacturing | Synthesis of protected non-natural amino acids | Employed as a fine chemical intermediate to prepare modified amino acids with tailored side-chain functionalities for drug molecule or probe design |
| Drug development | Construction of protease-resistant peptide therapeutics | Leverages D-lysine to enhance peptide stability against proteolytic degradation; combined with orthogonal protection strategies to enable sequence-specific synthesis of complex peptides |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorption at specified wavelength using reverse-phase chromatography with calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., deprotected, di-Boc, or hydrolyzed forms) via gradient HPLC separation. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DMF, THF, ethyl acetate) using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water by electrochemical titration with iodine-based reagent reacting stoichiometrically with water. |
| Optical Purity (Enantiomeric Excess) | Chiral HPLC | Separates D- and L-enantiomers on a chiral stationary phase and quantifies D-lysine content relative to racemate. |
| Heavy Metals | ICP-MS | Quantifies trace metal impurities (e.g., Pd, Ni, Fe) after acid digestion using inductively coupled plasma mass spectrometry. |
| Residual Palladium | ICP-MS | Specific quantification of palladium catalyst residues from Fmoc/Boc protection steps using isotope-specific detection. |
| Loss on Drying | Gravimetric Analysis | Measures volatile matter by weight loss after controlled heating under defined temperature and vacuum conditions. |
| pH (1% w/v aqueous suspension) | pH Meter | Determines acidity/basicity of suspension in water using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder particle size via light scattering pattern generated by dispersed particles in air stream. |
| Residual Chloride | Ion Chromatography | Quantifies chloride ions from synthesis or workup using anion-exchange column with conductivity detection. |
| Microbial Contamination | Membrane Filtration | Detects viable aerobic microorganisms by filtration, membrane transfer to agar media, and colony enumeration after incubation. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128°C to 134°C |
| Optical Rotation | -28° to -34° (c=1, in 1M HCl) |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.