N-(TERT-BUTOXYCARBONYL)-L-PROLINE N'-METHOXY-N'-METHYLAMIDE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 115186-37-3 |
| Product name | N-(TERT-BUTOXYCARBONYL)-L-PROLINE N'-METHOXY-N'-METHYLAMIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-(TERT-BUTOXYCARBONYL)-L-PROLINE N'-METHOXY-N'-METHYLAMIDE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-(TERT-BUTOXYCARBONYL)-L-PROLINE N'-METHOXY-N'-METHYLAMIDE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-(TERT-BUTOXYCARBONYL)-L-PROLINE N'-METHOXY-N'-METHYLAMIDE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis intermediate for protease inhibitors | Used as an organic synthesis intermediate to construct biologically active peptide-based drug molecules in solid-phase or solution-phase peptide synthesis |
| Biochemical Research | Enzyme substrate analog design | Applied to mimic natural peptide chain structures for studying protease mechanisms of action and selective inhibition properties |
| Pharmaceutical R&D | Antiviral drug development | Employed as a key chiral building block to introduce specific stereochemistry in the development of protease inhibitors against HIV or other viruses |
Manufacturing Quality Control of N-(TERT-BUTOXYCARBONYL)-L-PROLINE N'-METHOXY-N'-METHYLAMIDE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 210 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification and control based on ICH Q3A/B thresholds. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., DMF, DCM, MeOH) per ICH Q3C. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water by stoichiometric reaction. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific optical rotation using a polarimeter at 20 C and sodium D-line (589 nm) to confirm chiral integrity. |
| Heavy Metals | ICP-MS | Quantitative multi-element analysis after acid digestion; detection of Pb, Cd, Hg, As, Ni at sub-ppb levels per ICH Q3D. |
| Residual Palladium | ICP-MS | Specific quantification of Pd residue from catalytic coupling steps using isotope-dilution ICP-MS. |
| Chloride Content | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous solution after sample dissolution and dilution. |
| pH (1% w/v aqueous solution) | Potentiometric pH Measurement | Direct measurement using calibrated pH electrode in a standardized aqueous suspension. |
| Loss on Drying | Gravimetric Thermogravimetry | Weight loss measured after drying under controlled temperature and vacuum per USP <731>. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser scattering to determine D10, D50, D90 values. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms and absence testing for specified pathogens per USP <61> and <62>. |
Technical Specifications of N-(TERT-BUTOXYCARBONYL)-L-PROLINE N'-METHOXY-N'-METHYLAMIDE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -38.0° ± 2.0° (c=1, in DMF) |
| Melting Point | 145–149°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-(TERT-BUTOXYCARBONYL)-L-PROLINE N'-METHOXY-N'-METHYLAMIDE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-(TERT-BUTOXYCARBONYL)-L-PROLINE N'-METHOXY-N'-METHYLAMIDE
Safety Information of N-(TERT-BUTOXYCARBONYL)-L-PROLINE N'-METHOXY-N'-METHYLAMIDE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of N-(TERT-BUTOXYCARBONYL)-L-PROLINE N'-METHOXY-N'-METHYLAMIDE
Industrial N-(TERT-BUTOXYCARBONYL)-L-PROLINE N'-METHOXY-N'-METHYLAMIDE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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