China Factory Direct
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| CAS number | 1156491-10-9 |
| Product name | (1R trans)-2-(3,4-difluorophenyl)cyclopropane amine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceuticals | Pharmaceutical Intermediates | Used in the synthesis of compounds exhibiting antidepressant and anxiolytic activity; serves as a key intermediate for novel psychiatric drugs. |
| Test Item | Common Test Method | Method Overview |
|---|---|---|
| Identity | Infrared Spectroscopy (IR) | Confirm molecular functional groups by comparing the sample's infrared absorption spectrum with that of a reference standard or reference spectrum. |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Verify molecular structure and stereochemistry (e.g., 1R,2S configuration) based on resonance signals of hydrogen atoms in a magnetic field. | |
| Mass Spectrometry (MS) | Determine molecular ion peak and fragment ions to confirm molecular weight and structural information. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Quantify the main component using a reversed-phase column and UV detector, typically via external standard method or area normalization method. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Simultaneously separate and detect process impurities, degradation products, etc., under assay conditions, with appropriate acceptance limits. |
| Enantiomeric Purity / Optical Purity | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Use chiral stationary phase columns to separate the (1R,2S) isomer from other stereoisomers and assess optical purity. |
| Water Content | Karl Fischer Titration | Quantify water content in the sample through a specific chemical reaction; suitable for water-sensitive pharmaceuticals. |
| Residual Solvents | Gas Chromatography (GC) | Detect residual organic solvents (e.g., methanol, ethanol, dichloromethane) from synthesis using headspace or direct injection. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Measure residual levels of heavy metal elements such as lead, arsenic, mercury, and cadmium to ensure compliance with pharmacopoeial limits. |
| pH Value | pH Meter Method | Prepare an aqueous solution of defined concentration and measure its acidity or alkalinity using a calibrated pH meter to reflect the dissociation characteristics of the hydrochloride salt. |
| Appearance and Physical Characteristics | Visual Inspection | Observe physical properties such as color, crystal form, and odor; should be white to off-white crystalline powder. |
| Melting Point | Melting Point Apparatus | Determine the melting temperature range of the compound as an auxiliary indicator of purity and identity. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Optical Rotation | -25.0° to -29.0° (c=1, in 1M HCl) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.