3-CHLORO-4-TRIFLUOROMETHYL-BENZOIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 115754-20-6 |
| Product name | 3-CHLORO-4-TRIFLUOROMETHYL-BENZOIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-CHLORO-4-TRIFLUOROMETHYL-BENZOIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-CHLORO-4-TRIFLUOROMETHYL-BENZOIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-CHLORO-4-TRIFLUOROMETHYL-BENZOIC ACID
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate in the synthesis of the novel insecticide flonicamid | Participates in flonicamid synthesis via multi-step reactions, including acid chlorination, ammonolysis, and cyclization |
| Pharmaceuticals | Potential drug synthesis intermediate for constructing bioactive molecules containing trifluoromethyl-substituted aryl rings | Serves as an aryl ring substituent modification unit, participating in coupling reactions (e.g., Suzuki, Heck) or functional group transformations to construct candidate drug molecules |
Manufacturing Quality Control of 3-CHLORO-4-TRIFLUOROMETHYL-BENZOIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~230 nm, comparing peak area against a certified reference standard. |
| Related Substances (Impurities) | HPLC-UV/DAD | Separation and identification of structurally related impurities (e.g., isomers, dehalogenated, hydrolyzed by-products) using gradient HPLC with diode-array detection. |
| Residual Solvents | GC-FID | Quantification of volatile organic solvents (e.g., methanol, toluene, DMF) by gas chromatography with flame ionization detection, per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic elements (Pb, Cd, Hg, As, Ni) at trace levels using inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Content | Potentiometric Titration with AgNO₃ | Determination of inorganic chloride impurity via argentometric titration using silver nitrate and a silver indicator electrode. |
| Moisture Content | Karl Fischer Coulometric Titration | Precise water quantification based on electrochemical generation of iodine and stoichiometric reaction with water in anhydrous medium. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using calibrated capillary apparatus; deviation from literature value (148–150 °C) indicates purity or polymorphic issues. |
| Residue on Ignition | Gravimetric Analysis | Determination of non-volatile inorganic residue after controlled high-temperature ashing (700–800 °C) and weighing. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution using Mie scattering theory under controlled dispersion conditions. |
| Specific Optical Rotation | Polarimetry | Measurement of chiral impurity or enantiomeric excess (if applicable) using sodium D-line light at specified concentration and temperature. |
| pH of Aqueous Suspension | pH Meter | Determination of acidic character via pH measurement of a standardized suspension (e.g., 1% w/v in water), indicating residual acidity or salt formation. |
| Organic Volatile Impurities (OVI) | GC-MS | Identification and quantification of low-level process-related volatile organics using gas chromatography coupled with mass spectrometric detection. |
| Sulfated Ash | Gravimetric Analysis | Quantification of inorganic sulfate content after sulfuric acid treatment and high-temperature ignition, per USP <281>. |
Technical Specifications of 3-CHLORO-4-TRIFLUOROMETHYL-BENZOIC ACID
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 142–146 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-CHLORO-4-TRIFLUOROMETHYL-BENZOIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-CHLORO-4-TRIFLUOROMETHYL-BENZOIC ACID
Safety Information of 3-CHLORO-4-TRIFLUOROMETHYL-BENZOIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3-CHLORO-4-TRIFLUOROMETHYL-BENZOIC ACID
Industrial 3-CHLORO-4-TRIFLUOROMETHYL-BENZOIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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