China Factory Direct
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| CAS number | 115787-50-3 |
| Product name | 5-Bromoacetyl-2-hydroxybenzaldehyde |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate in the synthesis of antitumor agents (e.g., PARP inhibitor analogs) | Bromoacetylation of the phenolic hydroxyl group of 2-hydroxybenzaldehyde, followed by recrystallization for purification |
| Organic Synthesis | Building block for heterocyclic compounds containing both bromo and aldehyde functional groups (e.g., benzofuran and quinoline derivatives) | Participates in cyclization reactions (e.g., Pd-catalyzed C–O coupling or condensation cyclization) as a bifunctional synthon |
| Materials Science | Precursor for fluorescent sensing molecules and metal ion probes | The aldehyde group enables Schiff base condensation to introduce recognition moieties; the bromo group facilitates subsequent Suzuki or Heck coupling to modify conjugated structures |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~280 nm. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities (e.g., starting materials, intermediates, degradation products) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify residual solvents (e.g., acetone, ethyl acetate, DMF) per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS | Multi-element quantitative analysis of toxic elements (Pb, Cd, Hg, As) after acid digestion, offering sub-pptr detection sensitivity. |
| Moisture Content | Karl Fischer Titration | Coulometric or volumetric titration based on the stoichiometric reaction of iodine with water in a controlled anhydrous medium. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement via controlled heating; used for identity confirmation and purity assessment (sharp melting range indicates high purity). |
| Test Item | Specification |
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| Appearance | Brown solid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128–132°C |
| Identification (NMR) | Conforms to reference standard |
| Identification (IR) | Conforms to reference standard |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.