L-Lysine, N6-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]- Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1159680-21-3 |
| Product name | L-Lysine, N6-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]- |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1159680-21-3
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1159680-21-3 Supplier from China
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Industrial Applications of 1159680-21-3
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a protecting amino acid derivative in peptide synthesis to incorporate homoarginine residues and enable selective deprotection | Applied in solid-phase peptide synthesis (SPPS) using the Fmoc strategy for α-amino protection; the guanidino group is protected with a Pbf-like moiety (pentamethyl-dihydrobenzofuranyl sulfonyl), which is cleaved simultaneously under acidic conditions (e.g., TFA) |
| Biochemical Research | Used to synthesize biologically active peptides containing homoarginine for structure–function and cell-penetrating property studies | Employed as a building block during peptide chain assembly, participating in amide bond formation via standard coupling reagents (e.g., HBTU/DIPEA) |
| Medicinal Chemistry | Used to construct drug candidate molecules incorporating non-natural amino acids to enhance metabolic stability or target selectivity | Introduced as a modified amino acid in combinatorial chemistry or fragment-based synthesis, followed by purification and characterization (e.g., HPLC, MS) to obtain the target compound |
Manufacturing Quality Control of 1159680-21-3
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 260-280 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification and reporting of all impurities >0.1%. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., DMF, DCM, MeOH) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As, Ni) after acid digestion, using isotopic detection at sub-ppq sensitivity. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride anion using suppressed conductivity detection with carbonate/bicarbonate eluent. |
| Sulfonate Content | Acid-Base Titration | Back-titration of sulfonic acid group after alkaline hydrolysis using standardized NaOH and phenolphthalein endpoint. |
| Optical Rotation | [alpha]D Measurement | Determination of specific optical rotation using sodium D-line light source to confirm chiral integrity and enantiomeric purity. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion via laser scattering to report D10, D50, D90 values in micrometers. |
| Loss on Drying | Gravimetric Analysis | Weight loss measurement after drying at 105 C for 2 hours under vacuum, reflecting volatile and moisture content. |
| Residue on Ignition | Gravimetric Ashing | Mass of inorganic residue remaining after controlled high-temperature ashing (600 C), indicating inorganic impurities. |
| Microbial Limits | Membrane Filtration | Quantitative enumeration of aerobic bacteria, yeast, and mold using membrane filtration followed by culture on appropriate agar media. |
Technical Specifications of 1159680-21-3
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 185–189 °C |
| Optical Rotation | -7±2 ° (c=1, DMF) |
| Identification (NMR) | Conforms to structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1159680-21-3
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1159680-21-3
Packaging of 1159680-21-3
Industrial 1159680-21-3 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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