(3R)-(-)-3-Aminopyrrolidine dihydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 116183-81-4 |
| Product name | (3R)-(-)-3-Aminopyrrolidine dihydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (3R)-(-)-3-Aminopyrrolidine dihydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (3R)-(-)-3-Aminopyrrolidine dihydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (3R)-(-)-3-Aminopyrrolidine dihydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Pharmaceutical Intermediates | Used as a chiral building block in the synthesis of antibiotic agents (e.g., tobramycin derivatives) |
| Pharmaceutical Industry | Chiral Synthesis Raw Material | Applied to construct chiral drug molecules containing a pyrrolidine scaffold, providing the (R)-configured stereocenter |
| Pharmaceutical Industry | Drug Discovery and Development | Serves as a key structural unit in candidate drug screening libraries |
| Organic Synthesis | Asymmetric Synthesis Reagent | Participates in the synthesis of chiral catalysts or ligands |
Manufacturing Quality Control of (3R)-(-)-3-Aminopyrrolidine dihydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC with Chiral Column | Separation and quantification using a chiral stationary phase and UV detection at 210 nm |
| Enantiomeric Excess (ee) | Chiral HPLC | Comparison of peak areas of (R)- and (S)-enantiomers on a chiral column to calculate enantiomeric excess |
| Loss on Drying (LOD) | Gravimetric Thermogravimetry | Mass loss measured after heating at 105 C under vacuum for 2 hours |
| Residual Solvents | Gas Chromatography (GC-FID) | Quantification of organic solvents (e.g., methanol, acetone, ethyl acetate) using flame ionization detection |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification after acid digestion using inductively coupled plasma mass spectrometry |
| Chloride Content | Potentiometric Titration with AgNO3 | Titration with silver nitrate using a silver indicator electrode; endpoint detected by potential change |
| pH of Aqueous Solution | pH Meter Measurement | Measurement of pH in a 1% w/v aqueous solution at 25 C using calibrated pH electrode |
| Water Content | Karl Fischer Coulometric Titration | Electrochemical quantification of water based on iodine generation and stoichiometric reaction with water |
| Related Substances | Reverse-Phase HPLC | Separation and quantification of impurities using C18 column and gradient UV detection |
| Residue on Ignition | Gravimetric Sulfated Ash | Mass of non-volatile residue after ignition at 600 C following sulfuric acid treatment |
| Optical Rotation | [alpha]D Measurement | Determination of specific rotation using sodium D-line light at specified concentration and path length |
| Microbial Limits | Membrane Filtration and Plate Count | Enumeration of aerobic microorganisms via filtration, membrane transfer, and incubation on soybean-casein digest agar |
Technical Specifications of (3R)-(-)-3-Aminopyrrolidine dihydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -1.3 to -0.9 deg (c=1, H2O) |
| Melting Point | 245 to 250 °C (decomposes) |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (3R)-(-)-3-Aminopyrrolidine dihydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (3R)-(-)-3-Aminopyrrolidine dihydrochloride
Safety Information of (3R)-(-)-3-Aminopyrrolidine dihydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (3R)-(-)-3-Aminopyrrolidine dihydrochloride
Industrial (3R)-(-)-3-Aminopyrrolidine dihydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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