China Factory Direct
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| CAS number | 116272-42-5 |
| Product name | 5-CHLORO-2-FLUOROIODOBENZENE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used to synthesize fluorinated and chlorinated aromatic drug molecules, including precursors for anticancer, anti-infective, and central nervous system agents | Multi-step organic synthesis processes, including palladium-catalyzed coupling reactions (e.g., Suzuki, Heck), nucleophilic substitution, and halogen exchange |
| Agrochemical Intermediates | Serves as a starting material for constructing fluorinated benzene ring structures in the development of novel insecticides or herbicides | Synthesis pathways including regioselective halogen substitution, Grignard reagent derivatization, and condensation with heterocyclic compounds |
| Organic Synthesis Reagents | Used as an arylating reagent to introduce the 2-fluoro-5-chlorophenyl moiety into complex molecules | Metal-catalyzed cross-coupling reactions (e.g., Buchwald–Hartwig amination, Sonogashira alkyne coupling) and radical arylations |
| Materials Science | Structural building block for synthesizing fluorinated functional materials, such as liquid crystal monomers and OLED intermediates | Multi-step functional group transformations, including deiodination, boronic esterification, and cyanation |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | GC-FID or GC-MS | Quantitative determination by comparison of peak area against a certified reference standard using gas chromatography with flame ionization or mass spectrometric detection. |
| Related Substances | HPLC-UV | Separation and quantification of impurities based on retention time and UV absorbance relative to the main peak. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents using headspace gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of iodine with water in a controlled anhydrous environment. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of trace metal contaminants after acid digestion, based on mass-to-charge ratio. |
| Iodine Content | Potentiometric Titration with Sodium Thiosulfate | Redox titration where iodine is reduced to iodide and titrated with standardized thiosulfate solution using a redox indicator electrode. |
| Chlorine Content | Oxygen Flask Combustion followed by Ion Chromatography | Combustion of sample to convert chlorine to chloride ion, followed by separation and quantification via ion chromatography. |
| Fluorine Content | Ion Selective Electrode (ISE) after Alkaline Fusion | Alkaline fusion converts fluorine to fluoride ion, which is measured potentiometrically using a fluoride-selective electrode. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as solid-to-liquid phase change under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting. |
| Acid Value | Acid-Base Titration with NaOH | Neutralization of acidic impurities using standardized sodium hydroxide solution and phenolphthalein indicator. |
| Residue on Ignition | Gravimetric Analysis | Determination of non-volatile inorganic residue after high-temperature incineration and weighing. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 72-76°C |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.