China Factory Direct
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| CAS number | 116369-25-6 |
| Product name | 4-BROMO-3-TRIFLUOROMETHOXY-PHENYLAMINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Intermediates for synthesizing antitumor and antiviral drugs | Used as a fluorinated aromatic amine in coupling or substitution reactions to construct target molecular frameworks |
| Pesticide Chemicals | Synthetic intermediates for agrochemicals such as insecticides and herbicides | Applied to introduce the trifluoroethoxyaniline structural motif, enhancing biological activity and metabolic stability |
| Organic Synthesis | Building block for fluorinated fine chemicals | Derivatized via modern synthetic methods including Sandmeyer reaction, Suzuki coupling, and Buchwald–Hartwig amination |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances (Impurities) | HPLC-UV/DAD | Separation and identification of structurally related impurities (e.g., residual bromination intermediates, hydrolysis products) via gradient HPLC with diode-array detection. |
| Residual Solvents | GC-FID | Quantification of volatile organic solvents (e.g., toluene, THF, methanol) using capillary GC with flame ionization detection and internal standard calibration. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water content based on the stoichiometric reaction of iodine with water in anhydrous pyridine/methanol medium. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element trace metal quantification after acid digestion, leveraging high sensitivity and isotopic resolution for regulatory compliance (e.g., ICH Q3D). |
| Residue on Ignition | Gravimetric Analysis | Measurement of inorganic ash content after controlled high-temperature incineration (700–800 °C) and precise weighing of residual residue. |
| Melting Point | Capillary Melting Point Apparatus | Determination of crystalline phase transition temperature using calibrated digital apparatus with controlled heating rate (1–2 °C/min). |
| Chloride Impurity | Ion Chromatography (IC) | Quantitative analysis of chloride ions via suppressed conductivity detection after separation on an anion-exchange column with carbonate eluent. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to assess chiral purity (though compound is achiral, confirms absence of optically active contaminants). |
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.5% (GC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 45–49°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.