Z-TYR-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1164-16-5 |
| Product name | Z-TYR-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Z-TYR-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Z-TYR-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Z-TYR-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key chiral intermediate for the synthesis of the antiplatelet drug ticagrelor | Introduces the pyrimidino-fused ring structure into the ticagrelor synthesis pathway via multi-step reactions, including amide bond formation, cyclization, and subsequent functional group transformations of CBZ-L-tyrosine |
| Peptide Synthesis | Protected L-tyrosine derivative used in coupling steps during solid-phase or solution-phase peptide chain elongation | Undergoes amidation with amine components under basic conditions (e.g., DIPEA/DMF) using coupling reagents such as DCC/HOBt, DIC/Oxyma, or HATU |
| Biochemical Research | Modified amino acid precursor for enzyme inhibitor screening, protein kinase substrate probes, and phosphorylation site studies | After selective deprotection (e.g., CBZ removal with H₂/Pd-C), undergoes further phosphorylation or fluorescent labeling for kinase activity assays or cellular imaging |
Manufacturing Quality Control of Z-TYR-OH
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 275 nm. |
| Related Substances | HPLC-UV | Separation and detection of structurally related impurities (e.g., CBZ-Gly, tyrosine, des-CBZ tyrosine) using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., methanol, ethyl acetate, toluene) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction. |
| Heavy Metals | ICP-OES | Multi-element detection of Pb, Cd, Hg, As, and other heavy metals after acid digestion, based on atomic emission intensity. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Determination of inorganic residue after controlled combustion at 600-700 C, followed by weighing of the residual ash. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific rotation using a polarimeter at 20 C with sodium D-line (589 nm) to confirm chiral integrity. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample to determine volume-based particle size distribution from light scattering patterns. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of pH in a 1% w/v aqueous suspension using calibrated pH electrode and buffer standards. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic mesophilic bacteria and detection of specified pathogens (e.g., E. coli, S. aureus) by filtration and agar culture. |
| Residual Palladium | ICP-MS | Ultra-trace quantification of palladium catalyst residues after microwave digestion, using mass spectrometry detection. |
Technical Specifications of Z-TYR-OH
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 215-219°C |
| Optical Rotation | +8.0 to +12.0° (c=1, in 1M HCl) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Z-TYR-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Z-TYR-OH
Packaging of Z-TYR-OH
Industrial Z-TYR-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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