China Factory Direct
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| CAS number | 116529-31-8 |
| Product name | 4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral intermediate for synthesizing antibiotics (e.g., thienamycins) | Used to construct the sulfur-containing heterocyclic β-lactam antibiotic scaffold via reduction of cyclic sulfoxide derivatives followed by hydrochloride salt formation |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at characteristic wavelength, calibrated against reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification by retention time comparison and/or spiked reference standards. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents based on calibrated response factors. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generation in pyridine-free reagent to determine water content stoichiometrically. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with conductivity detection. |
| Heavy Metals | ICP-OES | Multi-element detection after acid digestion; quantification based on emission intensities at element-specific wavelengths. |
| pH (1% aqueous solution) | Potentiometric pH Measurement | Measurement of hydrogen ion activity using calibrated glass electrode in aqueous suspension/solution. |
| Loss on Drying | Gravimetric Analysis | Mass loss determined after drying under controlled temperature and vacuum or nitrogen purge. |
| Residue on Ignition | Gravimetric Ashing | Weight of non-volatile residue remaining after high-temperature incineration in a muffle furnace. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity as function of angle to derive particle size distribution in dispersed sample. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution of chiral compound at specified concentration and path length. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms after filtration, membrane transfer to culture media, and incubation per pharmacopeial guidelines. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.