(R)-3-Amino-1,2,3,4-tetrahydrocarbazole Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 116650-33-0 |
| Product name | (R)-3-Amino-1,2,3,4-tetrahydrocarbazole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-3-Amino-1,2,3,4-tetrahydrocarbazole
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-3-Amino-1,2,3,4-tetrahydrocarbazole Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-3-Amino-1,2,3,4-tetrahydrocarbazole
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral intermediates for synthesizing antidepressants (e.g., vilazodone) | Preparation of the key vilazodone intermediate via asymmetric catalytic hydrogenation or chiral resolution |
| Pharmaceuticals | Structural building block for 5-HT1A receptor partial agonist candidates | Introduction of the carbazole scaffold as a chiral synthon in multistep organic synthesis |
| Fine Chemicals | Precursor to chiral ligands or catalysts | Synthesis of novel chiral phosphine ligands via derivatization reactions such as sulfonylation and phosphination |
Manufacturing Quality Control of (R)-3-Amino-1,2,3,4-tetrahydrocarbazole
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~220–280 nm, comparing peak area against a certified reference standard. |
| Enantiomeric Purity | Chiral HPLC | Separation and quantification of (R)- and (S)-enantiomers using a chiral stationary phase; enantiomeric excess (ee) calculated from peak areas. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common organic solvents (e.g., methanol, ethyl acetate, toluene) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, with detection at sub-pptr levels. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and conductivity detection of chloride ions in aqueous extract; quantified against chloride standard calibration. |
| Related Substances | HPLC-UV (Forced Degradation Study) | Detection and quantification of structurally related impurities (e.g., deaminated, oxidized, or dimeric by-products) under stressed conditions (acid/base/oxidative/thermal). |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using calibrated capillary apparatus per USP <741>; indicates crystallinity and identity consistency. |
| Specific Optical Rotation | [α]D Measurement | Polarimetric determination at 589 nm (Na D-line) to confirm chiral integrity and batch-to-batch consistency of optical activity. |
| Residue on Ignition | Gravimetric Analysis (Sulfated Ash) | Ignition at 700–800 °C followed by gravimetric measurement of non-volatile inorganic residue, per USP <281>. |
Technical Specifications of (R)-3-Amino-1,2,3,4-tetrahydrocarbazole
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=99.0% (HPLC) |
| Optical Rotation | +62.0 to +63.5° (c=1, in methanol) |
| Melting Point | 148.0 to 152.0°C |
| Total Impurities | <=1.0% (HPLC) |
| Single Impurity | <=0.3% (HPLC) |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-3-Amino-1,2,3,4-tetrahydrocarbazole
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-3-Amino-1,2,3,4-tetrahydrocarbazole
Safety Information of (R)-3-Amino-1,2,3,4-tetrahydrocarbazole
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of (R)-3-Amino-1,2,3,4-tetrahydrocarbazole
Industrial (R)-3-Amino-1,2,3,4-tetrahydrocarbazole Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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