China Factory Direct
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| CAS number | 116751-24-7 |
| Product name | 3-Hydroxy-2,4,5-trifluorobenzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for novel anticoagulants (e.g., Factor Xa inhibitors) | Used in the preparation of active pharmaceutical ingredients (APIs) via diazotization, hydrolysis, and fluorination |
| Agrochemicals | Synthetic intermediate for fluorinated herbicides and fungicides | Applied to construct trifluoromethylphenyl ring structures, enhancing metabolic stability and target binding affinity |
| Materials | Building block for high-performance liquid crystal monomers and organic light-emitting diode (OLED) functional materials | Employed in esterification/amidation coupling reactions to introduce rigid fluorinated aryl rings, enabling control over molecular polarity and thermal stability |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection. |
| Related Substances | HPLC-UV | Separation and quantification of impurities by retention time and response relative to the main peak under validated gradient conditions. |
| Residual Solvents | GC-FID | Detection and quantification of volatile organic solvents using gas chromatography with flame ionization detection and external calibration. |
| Water Content | Karl Fischer Titration | Electrochemical titration measuring water via iodine-sulfur dioxide reaction in a methanol-based reagent system. |
| Heavy Metals | ICP-MS | Multi-element quantification of trace metals (e.g., Pb, Cd, Hg, As) using inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity-based detection of chloride anions using anion-exchange column and suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Residue weight measurement after high-temperature incineration of sample in presence of sulfuric acid. |
| Optical Rotation | [a]D Measurement | Determination of specific rotation using sodium D-line light source in a polarimeter to assess chiral purity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observation via capillary tube method following pharmacopeial guidelines (e.g., USP <741>). |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined saturated aqueous suspension using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution based on angular scattering intensity of laser light through dispersed sample. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residue using inductively coupled plasma optical emission spectrometry after microwave-assisted digestion. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 178–182°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.