Z-ALA-ONP Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1168-87-2 |
| Product name | Z-ALA-ONP |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Z-ALA-ONP
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Z-ALA-ONP Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Z-ALA-ONP
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Peptide drug synthesis | Used as an N-protected alanine active ester in solid-phase or solution-phase peptide synthesis, enabling amide bond formation via condensation with amino components. |
| Biochemical Research | Enzyme activity assay | Serves as a substrate for protease (e.g., trypsin, chymotrypsin) activity assays and kinetic studies; quantified colorimetrically by measuring p-nitrophenol release upon hydrolysis. |
| Biochemistry | Research on amino acid protecting groups | Applied in studying the protection and deprotection behavior of benzyloxycarbonyl (Z or Cbz) groups to optimize amino acid functional group protection strategies. |
| Pharmaceutical Intermediates | Active ester synthesis process development | Employed in developing high-efficiency amino acid active ester preparation processes with minimal racemization, serving as an effective coupling agent for amide bond formation. |
Manufacturing Quality Control of Z-ALA-ONP
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and detection of structurally related impurities (e.g., hydrolysis products, isomers) using gradient HPLC with UV monitoring. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., DMF, toluene, methanol) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of iodine with water in a pyridine-methanol solvent system. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions following sample dissolution and filtration. |
| Optical Rotation | [alpha]D Measurement | Determination of specific optical rotation using a polarimeter at 20 C and sodium D-line (589 nm) to confirm chiral integrity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observation via controlled heating of a capillary-packed sample to determine onset and range of melting. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light and against standard references. |
| Loss on Drying | Gravimetric Analysis | Mass loss measurement after drying under specified temperature and vacuum conditions for fixed duration. |
| Residue on Ignition | Gravimetric Analysis | Weighing of non-volatile inorganic residue remaining after high-temperature ashing in a muffle furnace. |
| pH of Solution | Potentiometric pH Measurement | Electrochemical determination of hydrogen ion activity in a standardized aqueous or aqueous-organic solution using calibrated pH electrode. |
Technical Specifications of Z-ALA-ONP
| Test Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 75–79 °C |
| Optical Rotation | -38.0 to -36.0 ° (c=1, in CHCl3) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Z-ALA-ONP
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Z-ALA-ONP
Packaging of Z-ALA-ONP
Industrial Z-ALA-ONP Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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