(S)-tert-butyl 3-(4-aMinophenyl)piperidine-1-carboxylate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1171197-20-8 |
| Product name | (S)-tert-butyl 3-(4-aMinophenyl)piperidine-1-carboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (S)-tert-butyl 3-(4-aMinophenyl)piperidine-1-carboxylate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (S)-tert-butyl 3-(4-aMinophenyl)piperidine-1-carboxylate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (S)-tert-butyl 3-(4-aMinophenyl)piperidine-1-carboxylate
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceutical R&D | Pharmaceutical intermediate | Used as a key intermediate in synthesizing bioactive piperidine-containing drugs for antidepressant or anxiolytic drug development |
| Chemical synthesis | Organic synthesis building block | Applied as a chiral building unit in organic synthesis, participating in various synthetic routes including coupling and amination reactions |
| Research | New compound development | Employed in constructing complex molecular architectures, such as polycyclic compounds or chiral amine derivatives |
Manufacturing Quality Control of (S)-tert-butyl 3-(4-aMinophenyl)piperidine-1-carboxylate
| Test Item | Common Testing Method | Method Description |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state (e.g., white to off-white powder), and check for visible impurities or lumps. |
| Identification | Infrared Spectroscopy (FTIR) | Compare the sample with a reference spectrum to confirm characteristic functional group absorption peaks (e.g., N-H, C=O, aromatic C=C). |
| Nuclear Magnetic Resonance Spectroscopy (¹H NMR, ¹³C NMR) | Analyze proton and carbon chemical shifts and coupling constants via hydrogen and carbon spectra to confirm stereochemistry and substitution patterns. | |
| Mass Spectrometry (MS or HRMS) | Determine molecular ion peak ([M+H]+) to verify whether the measured molecular weight matches the theoretical value, assisting in structural confirmation. | |
| Purity/Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase C18 column with a UV detector (typically at 254 nm or 280 nm); calculate the content of the main component using external standard method or area normalization method. |
| Impurity Analysis | HPLC-DAD / LC-MS | Detect related substances (e.g., synthetic intermediates, degradation products, isomers), using gradient elution for separation and qualitative and quantitative analysis. |
| Water Content | Karl Fischer Titration | Accurately measure the total amount of bound and free water in the sample, suitable for API quality control. |
| Residual Solvents | Gas Chromatography (GC) | Detect residual solvents such as methanol, ethanol, dichloromethane, ethyl acetate according to ICH guidelines using an FID detector. |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | Detect toxic elements such as lead, cadmium, mercury, and arsenic to ensure compliance with pharmacopoeia limits. |
| Melting Point | Melting Point Apparatus | Determine the melting temperature range using capillary method, used to initially assess purity and consistency. |
| Optical Rotation | Polarimeter Measurement | Measure optical rotation under specific wavelength (e.g., sodium D line at 589 nm) and concentration to verify chirality purity (S configuration). |
| Particle Size Distribution (if applicable) | Laser Diffraction Particle Size Analysis (LDI) | If used as raw material for formulations, particle size distribution must be controlled to ensure solubility and bioavailability. |
| Thermal Stability | Differential Scanning Calorimetry (DSC) | Analyze melting behavior, polymorphic transitions, or decomposition temperatures to evaluate thermal stability and crystallinity. |
| Polymorphism Analysis | X-ray Powder Diffraction (XRPD) | Identify the presence of polymorphs and ensure batch-to-batch polymorphic consistency, especially critical for solid dosage forms. |
Technical Specifications of (S)-tert-butyl 3-(4-aMinophenyl)piperidine-1-carboxylate
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -75.0 to -65.0 deg (c=1, in CHCl3) |
| Melting Point | 148 to 152 °C |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (S)-tert-butyl 3-(4-aMinophenyl)piperidine-1-carboxylate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (S)-tert-butyl 3-(4-aMinophenyl)piperidine-1-carboxylate
Safety Information of (S)-tert-butyl 3-(4-aMinophenyl)piperidine-1-carboxylate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (S)-tert-butyl 3-(4-aMinophenyl)piperidine-1-carboxylate
Industrial (S)-tert-butyl 3-(4-aMinophenyl)piperidine-1-carboxylate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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