2-Chloro-4-iodonicotinonitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1171919-75-7 |
| Product name | 2-Chloro-4-iodonicotinonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Chloro-4-iodonicotinonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Chloro-4-iodonicotinonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Chloro-4-iodonicotinonitrile
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of antitumor agents (e.g., BRAF inhibitors) | Used to construct complex molecular frameworks via nucleophilic substitution, Suzuki coupling, and related reactions |
| Agrochemicals | Precursor for active ingredients in novel herbicides or insecticides | Applied to introduce target functional groups through halogen exchange, cyano group transformation, and related steps |
| Chemical Research | Synthetic building block for iodinated heterocyclic compounds | Employed in transition metal-catalyzed cross-coupling reactions (e.g., Sonogashira, Heck reactions) |
Manufacturing Quality Control of 2-Chloro-4-iodonicotinonitrile
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 220-254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification via retention time matching and threshold-based reporting. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common organic solvents (e.g., acetone, methanol, toluene) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Iodine Content | Potentiometric Titration | Redox titration with sodium thiosulfate following oxidative liberation of iodine, monitored by iodide-selective electrode. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light and against standard references. |
| Particle Size Distribution | Laser Diffraction | Measurement of particle size distribution in dry or dispersed state using Mie scattering theory and optical diffraction. |
| Bulk Density | Tap Density Tester | Determination of mass per unit volume after standardized tapping per USP <616> for powder flow characterization. |
| Organic Volatile Impurities (OVI) | GC-MS | Targeted and non-targeted screening of residual process-related organics using gas chromatography-mass spectrometry. |
Technical Specifications of 2-Chloro-4-iodonicotinonitrile
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 102–106°C |
| Identification (NMR) | Conforms to reference standard |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Chloro-4-iodonicotinonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Chloro-4-iodonicotinonitrile
Safety Information of 2-Chloro-4-iodonicotinonitrile
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 2-Chloro-4-iodonicotinonitrile
Industrial 2-Chloro-4-iodonicotinonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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