3-Amino-3-(3-fluorophenyl)propanoic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 117391-51-2 |
| Product name | 3-Amino-3-(3-fluorophenyl)propanoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-Amino-3-(3-fluorophenyl)propanoic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-Amino-3-(3-fluorophenyl)propanoic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-Amino-3-(3-fluorophenyl)propanoic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing neuropharmacological agents, including antidepressants and 5-HT receptor modulators | Used as a chiral building block in multistep coupling and cyclization reactions; commonly employed in API synthesis following amidation, reductive amination, or chiral resolution |
| Pharmaceuticals | Chiral synthetic building block for preparing fluorinated phenylalanine derivatives | Applied as a substrate in palladium-catalyzed cross-coupling or enzyme-catalyzed asymmetric transformations to introduce the 3-fluorophenyl and β-amino acid structural motifs |
| Fine Chemicals | Organic synthesis reagent for constructing fluorinated β-amino acid scaffolds | Functionalized via standard amino acid operations, including decarboxylation, ester hydrolysis, and N-protection/deprotection |
Manufacturing Quality Control of 3-Amino-3-(3-fluorophenyl)propanoic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 210-230 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common organic solvents (e.g., methanol, acetone, ethyl acetate) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent where water reacts stoichiometrically to determine total moisture content. |
| Optical Rotation | [a]D Measurement | Measurement of specific rotation using a polarimeter at 20-25 C and sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-MS | Quantification of trace metal impurities (e.g., Pb, Cd, Ni, Fe) after acid digestion using inductively coupled plasma mass spectrometry with isotope dilution or external calibration. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride anion using suppressed conductivity detection after aqueous extraction and filtration. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 600-700 C followed by weighing of non-volatile inorganic residue after sulfuric acid treatment. |
| pH (1% w/v aqueous solution) | pH Potentiometry | Measurement using calibrated pH electrode in a saturated or 1% aqueous suspension to assess acidic/basic character and potential degradation. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid-to-liquid phase transition occurs, indicating purity and identity via comparison to reference standard. |
| Residue on Ignition | Gravimetric Analysis | Weighing of inorganic residue remaining after ignition at 700-750 C, reflecting non-volatile inorganic contaminants. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) per pharmacopeial methods using selective media and incubation. |
Technical Specifications of 3-Amino-3-(3-fluorophenyl)propanoic acid
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 210–215 °C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-Amino-3-(3-fluorophenyl)propanoic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-Amino-3-(3-fluorophenyl)propanoic acid
Safety Information of 3-Amino-3-(3-fluorophenyl)propanoic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3-Amino-3-(3-fluorophenyl)propanoic acid
Industrial 3-Amino-3-(3-fluorophenyl)propanoic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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