China Factory Direct
|
|
| CAS number | 117519-08-1 |
| Product name | 2-Chloro-3-Nitro-6-Trifluoromethyl Pyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Used as an insecticidal intermediate for synthesizing novel neonicotinoid insecticides such as flonicamid | Serves as a key intermediate in multistep organic synthesis, typically undergoing functional group transformations via nucleophilic substitution or reduction reactions |
| Pharmaceuticals | Used as a pharmaceutical synthetic intermediate to construct bioactive molecules containing a trifluoromethylpyridine moiety | Employed in medicinal chemistry for heterocyclic scaffold construction and participates in coupling reactions (e.g., Suzuki, Buchwald–Hartwig) to introduce pharmacophores |
| Fine Chemicals | Used as a precursor for synthesizing high-performance materials or functional chemicals | Converted into high-value fine chemicals via reactions such as nitro group reduction and chloro group substitution |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV against qualified reference standards or threshold-based reporting. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generation in pyridine-free reagent to determine water by coulometric or volumetric endpoint detection. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using isotopic mass spectrometry for sub-ppq sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract, calibrated against NaCl standards. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 700-800 C followed by weighing of non-volatile inorganic residue after sulfuric acid treatment. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed via optical detection as solid converts to liquid, compared to pharmacopeial reference material. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity across angular ranges to calculate volume-based particle size distribution in dispersed slurry. |
| Bulk Density | ASTM D1895 | Measurement of mass per unit volume of freely settled powder in a standardized cylinder under controlled tapping conditions. |
| Loss on Drying | Thermogravimetric Analysis | Mass loss measured gravimetrically after heating sample at 105 C for 2 hours under dry air or nitrogen purge. |
| Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution, indicating chiral purity if applicable (though compound is achiral, used for trace chiral contaminants). |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 78-82°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.