2-METHYL-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 117724-63-7 |
| Product name | 2-METHYL-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-METHYL-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-METHYL-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-METHYL-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of antiviral drugs (e.g., Favipiravir) | Thiazole ring formation via multistep organic synthesis, followed by esterification or hydrolysis for subsequent chemical modification |
| Agrochemicals | Intermediate for synthesizing fluorinated pesticides or plant growth regulators | Enhancement of bioactivity through lipophilic trifluoromethyl group incorporation; active molecular scaffolds introduced via condensation, halogenation, and related reactions |
| Chemical R&D | Building block for fluorinated heterocyclic compounds or specialty chemicals | Used in laboratory- or pilot-scale studies to explore novel reaction pathways or synthesize new functional materials |
Manufacturing Quality Control of 2-METHYL-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLIC ACID
| Detection Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and visible impurities under natural light or standard illumination. |
| Purity (Main Component Content) | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with an appropriate mobile phase (e.g., acetonitrile-water or buffer-containing system) for gradient or isocratic elution. Detect using UV detector (e.g., 210–254 nm), and calculate main component content by external standard method or area normalization method. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Same conditions as purity determination; detect and quantify related substances (e.g., synthesis intermediates, degradation products) by comparison with reference standards or self-control methods. |
| Residual Solvents | Gas Chromatography (GC) | Based on ICH guidelines, use headspace injection or direct solution injection. Separate common organic solvents (e.g., methanol, ethanol, dichloromethane, ethyl acetate) using capillary columns, and quantitate with FID detection. |
| Water Content | Karl Fischer Titration | Utilize the quantitative reaction between iodine and sulfur dioxide in the presence of pyridine and methanol to react with water. Determine moisture content using coulometric or volumetric Karl Fischer titration. |
| Melting Point | Capillary Melting Point Determination | Load the sample into a capillary tube and gradually heat it in a melting point apparatus. Observe initial and complete melting temperatures to determine if the melting range meets specifications. |
| Infrared Spectroscopy (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Acquire sample IR spectra using potassium bromide (KBr) pellet method or ATR accessory, and compare with reference spectrum to confirm molecular structural features and functional groups. |
| Nuclear Magnetic Resonance (NMR) | ¹H-NMR and/or ¹⁹F-NMR | Dissolve the sample in deuterated solvent (e.g., DMSO-d6), and analyze using a nuclear magnetic resonance spectrometer to verify compound structure and purity. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Method | Treat the sample with sulfuric acid, then incinerate at high temperature until constant weight. Weigh the residue to calculate the content of non-volatile inorganic impurities. |
| Heavy Metals | Sulfide Colorimetry (e.g., Chinese Pharmacopoeia Method) | After sample digestion, react with sodium sulfide under acidic conditions to form colored precipitates. Quantify total lead and other heavy metals by colorimetric analysis. |
Technical Specifications of 2-METHYL-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLIC ACID
| Test Item | Specification |
|---|---|
| Appearance | White to light yellow crystalline powder |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 142–146 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-METHYL-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-METHYL-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLIC ACID
Safety Information of 2-METHYL-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-METHYL-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLIC ACID
Industrial 2-METHYL-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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