China Factory Direct
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| CAS number | 118-00-3 |
| Product name | 118-00-3 |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthetic intermediate for antiviral drugs | Used as a precursor to nucleoside analogues in the chemical synthesis of antiviral agents |
| Food | Flavor enhancer (umami enhancer) | Applied in combination with disodium inosinate to enhance umami taste, commonly used in seasoning production |
| Biotechnology | Raw material for RNA synthesis | Applied in in vitro transcription or RNA fragment synthesis as a guanine base donor |
| Cosmetics | Skin-conditioning agent | Incorporated into skincare formulations to support skin metabolism and repair functions |
| Research Reagents | Molecular biology reagent | Used in enzymology studies, analysis of nucleic acid metabolic pathways, and cell culture experiments |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identification | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Utilizes the characteristic absorption peak of guanosine near 254 nm for qualitative analysis by comparing the spectral profile with a reference standard to confirm its chemical structure. |
| Infrared Spectroscopy (IR) | Determines the infrared absorption spectrum of the sample and compares it with a reference spectrum to confirm consistency of functional groups and molecular structure. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with a UV detector (254 nm) and a mobile phase of water-methanol or buffered salt to quantitatively determine guanosine content, offering high sensitivity and accuracy. |
| Impurity Detection (Related Substances) | High-Performance Liquid Chromatography (HPLC) | Uses HPLC with gradient elution to separate guanosine from its degradation products or synthetic impurities (e.g., guanine, hypoxanthine) to assess purity. |
| Water Content Determination | Karl Fischer Titration | Accurately measures water content in the sample; suitable for quality control of active pharmaceutical ingredients, available in volumetric and coulometric methods. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Drying Method | Heats the sample at a specified temperature and measures the percentage weight loss to assess volatile components and residual solvents. |
| Residue on Ignition (Fuse Residue) | Sulfation followed by high-temperature ignition | The sample is treated with sulfuric acid and then ignited at high temperature until constant weight, to determine the residual amount of non-volatile inorganic impurities. |
| Heavy Metal Testing | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Measures concentrations of heavy metals such as lead, cadmium, mercury, and arsenic; ICP-MS offers higher sensitivity and enables simultaneous multi-element detection. |
| Microbial Limit Test | Microbial Culture Method | Performs assays for total aerobic microbial count, mold, and yeast counts according to pharmacopoeial requirements, as well as tests for specified control organisms (e.g., Escherichia coli, Salmonella). |
| Bacterial Endotoxins | Limulus Amebocyte Lysate (LAL) Assay | Utilizes lysate from horseshoe crab amebocytes that react with endotoxins to produce gelation or color change; commonly used for injectable-grade raw materials. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 215-220°C |
| Optical Rotation | -72 to -80° (c=1, H2O) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.