China Factory Direct
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| CAS number | 118-12-7 |
| Product name | 1,3,3-Trimethyl-2-methyleneindoline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeElectronic GradeMaterial GradeReagent Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Dyes & Pigments | Key intermediate for photochromic dyes, used in the production of spirobenzopyran-based photosensitive materials | Condensation reaction with aldehydes or ketones to synthesize spiroindoline structures |
| Optical Materials | Manufacture of photochromic lenses, smart windows, and optical switching devices | Copolymerization or doping with spirobenzopyran derivatives into polymeric matrices to form responsive thin films |
| Analytical Chemistry | Photocontrolled molecular probe for visual detection of metal ions or pH | Construction of photoresponsive colorimetric or fluorescent sensing systems in solution |
| Biological Imaging | Photocontrolled labeling and dynamic tracking within live cells | Conversion to water-soluble derivatives followed by light-triggered structural change for spatiotemporally resolved imaging |
| Information Storage | Photosensitive layer material for rewritable optical storage media | Thin-film formation via spin-coating or vacuum deposition, enabling binary state switching under laser irradiation |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, state (such as white to white crystalline powder), and presence of foreign matter with the naked eye to determine whether its appearance meets the quality standards. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column, with methanol-water or acetonitrile-water as the mobile phase, and a UV detector (usually set at 254 nm or according to the maximum absorption wavelength of the compound) to detect the main peak area. Calculate the purity of the target compound, and use the total area of impurity peaks to evaluate the impurity content. |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Similar to the purity test, but using an external standard method or internal standard method. Compare with a known concentration reference standard to quantitatively determine the content of 1,3,3-trimethyl-2-methyleneindoline (usually expressed as %). |
| Melting Point | Melting Point Determination (Capillary Method or Digital Melting Point Apparatus) | Fill the sample into a capillary tube and heat it at a specified rate, recording the temperature range from initial melting to complete melting. Determine whether it meets the melting point range specified in literature or standards (approximately 100–103 °C for this compound). |
| Drying Loss | Thermogravimetric Analysis (TGA) or Atmospheric Drying Method | Dry the sample at a specified temperature (e.g., 105 °C) until constant weight is achieved, and measure the percentage of mass loss due to moisture or other volatile components to assess the drying degree. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace injection or direct injection methods, separate with a polar or non-polar capillary column, and detect residual organic solvents (such as toluene, dichloromethane, ethanol) using an FID detector. Control the limit according to ICH Q3C guidelines. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Under the conditions of the purity test, identify and quantify each impurity peak, including process impurities and degradation products, to ensure that the single impurity and total impurity content comply with pharmacopoeia or enterprise internal control standards. |
| Infrared Spectral Identification | Fourier Transform Infrared Spectroscopy (FT-IR) | Prepare KBr pellets or ATR samples, and measure the infrared absorption spectrum. Compare the characteristic absorption peaks (such as C=N, C=C, methyl groups) with the standard spectrum for structural confirmation and authenticity identification. |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Nuclear Magnetic Resonance Spectroscopy | Dissolve the sample in deuterated chloroform (CDCl₃) or other solvents, and measure the proton spectrum to confirm the chemical shift, integral area, and coupling constants of hydrogen atoms, used for structural verification and confirmation of high-purity samples. |
| Test Item | Specification |
|---|---|
| Appearance | Red to dark red or brown clear liquid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 45–49°C |
| Refractive Index (n20/D) | 1.615–1.625 |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.