Isatoic Anhydride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 118-48-9 |
| Product name | Isatoic Anhydride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Isatoic Anhydride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Isatoic Anhydride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Isatoic Anhydride
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Intermediate for synthesizing anticonvulsant and antiepileptic drugs (e.g., benzodiazepine derivatives) | Reacted with hydrazine or its derivatives to synthesize troparol analogues, or used in synthesizing phenobarbital intermediates |
| Pharmaceutical Industry | Key intermediate for producing nonsteroidal anti-inflammatory drugs (e.g., clofenamic acid, mefenamic acid) | Condensed with aromatic compounds such as o-chlorobenzoic acid, followed by further reactions |
| Agrochemical Industry | Raw material for synthesizing fungicides and insecticides (e.g., benalaxyl, phthalide-based fungicides) | Reacted with amines under alkaline conditions, or subjected to alkaline hydrolytic ring opening followed by structural modification and condensation |
| Dye Industry | Production of indigo and related dyes | Alkaline hydrolysis yields o-aminobenzoic acid for dye synthesis; alternatively, used directly as a color base in coupling reactions |
| Chemical Reagents | Colorimetric reagent for amino acid detection and biochemical analysis | Reacts with amino acids under specific conditions to form yellow or red compounds for spectrophotometric analysis or chromatographic detection |
| Fine Chemicals | Building block for synthesizing other fine chemicals and heterocyclic compounds | Derivatives prepared via electrocyclic reactions, hydrolytic ring opening, or reactions with nucleophiles (e.g., alcohols, amines) |
Manufacturing Quality Control of Isatoic Anhydride
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical form, and crystalline state to determine if they meet specifications (e.g., yellowish to orange-red crystalline powder). |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase chromatographic column with an appropriate mobile phase and a UV detector to separate and quantify the main component. |
| Melting Point | Capillary Melting Point Method | Determine the melting temperature range using a digital melting point apparatus or the traditional capillary method to assess purity and structural consistency. |
| Loss on Drying | Gravimetric Loss upon Drying | Dry the sample at a specified temperature (e.g., 105°C) to constant weight and calculate the percentage weight loss to evaluate moisture and volatile content. |
| Sulfated Ash | High-Temperature Ashing | Ignite the sample at high temperature (e.g., 600–800°C) to constant weight and measure the residual inorganic impurities. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After acid digestion, determine the levels of trace elements such as lead, arsenic, cadmium, and mercury to ensure compliance with pharmacopeial or industry safety standards. |
| Related Substances | HPLC Gradient Elution | Use a gradient elution program to separate and detect synthesis by-products or degradation impurities, controlling total impurity levels and the largest individual impurity. |
| pH Value (aqueous solution) | pH Meter Method | Prepare a solution of the sample at a defined concentration in water and measure its pH using a calibrated pH meter to assess hydrolysis or acidic impurities. |
| Solubility | Solubility Test | Observe solubility in specified solvents (e.g., ethanol, acetone, water) to confirm compliance with process or application requirements. |
| Structural Confirmation | Infrared Spectroscopy (IR), Nuclear Magnetic Resonance (NMR) | Compare characteristic absorption peaks or chemical shifts with reference spectra to verify that the molecular structure corresponds to the target compound, indigo carmine anhydride. |
Technical Specifications of Isatoic Anhydride
| Test Item | Specification |
|---|---|
| Appearance | White to almost white powder or crystals |
| Purity | >=98.0% (HPLC) |
| Melting Point | 135.0–139.0°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Isatoic Anhydride
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NMR Spectra of Isatoic Anhydride
Packaging of Isatoic Anhydride
Industrial Isatoic Anhydride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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