2'-Hydroxyacetophenone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 118-93-4 |
| Product name | 2'-Hydroxyacetophenone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2'-Hydroxyacetophenone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2'-Hydroxyacetophenone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2'-Hydroxyacetophenone
| Industry | Application | Process |
|---|---|---|
| Fragrance Industry | Used as a fragrance fixative and as an intermediate in the synthesis of vanillin, homosalol, and other aroma compounds | Vanillin is synthesized via condensation with chloroacetic acid, followed by cyclization and hydrolysis; homosalol is prepared from this compound as a starting material through oxidation and methylation |
| Pharmaceutical Industry | Employed as an intermediate in the synthesis of anti-inflammatory agents (e.g., sodium diclofenac), antiallergic drugs, and certain flavonoid-based pharmaceuticals | Participates in Claisen rearrangements and Friedel–Crafts acylations, or serves as a precursor for synthesizing benzodihydropyran derivatives |
| Pesticide Industry | Serves as a synthetic intermediate for fungicides (e.g., difenoconazole) and plant growth regulators | Triazole or benzofuran structures are constructed via multistep reactions including bromination, amination, and cyclization |
| Dye Industry | Applied as a modifier for auxochromes in the synthesis of azo dyes and fluorescent whitening agents | The hydroxyacetophenone structure is introduced via diazotization–coupling reactions to enhance dye photostability and substantivity |
| Organic Synthesis | Utilized as a Michael acceptor, ligand, and coordinating precursor for organometallic complexes | Undergoes Michael addition with reagents such as malonates and nitroalkanes under basic conditions; alternatively, forms β-keto alcohol-type complexes with transition metals (e.g., Pd, Ru) for catalytic applications |
Manufacturing Quality Control of 2'-Hydroxyacetophenone
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 275 nm, comparing peak area to a certified reference standard. |
| Appearance | Visual Inspection | Assessment of physical state and color against a white background under controlled lighting; acceptable as white to off-white crystalline solid. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated capillary method per USP <741>. |
| Loss on Drying | Gravimetric (105 C, 2 h) | Measurement of mass loss after drying under specified temperature and time, indicating volatile impurities and residual solvents. |
| Residue on Ignition | Gravimetric (Sulfated Ash) | Determination of non-volatile inorganic residue after ignition at 600-700 C following sulfuric acid treatment. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Sulfate Impurity | Turbidimetry | Formation of barium sulfate precipitate in acidic medium; quantification by measuring turbidity at 420 nm. |
| Heavy Metals (as Pb) | AAS (Flame or Graphite Furnace) | Atomic absorption spectroscopy after wet digestion and chelation, targeting total heavy metals expressed as lead. |
| Related Substances | HPLC-DAD | Identification and quantification of structurally related impurities using gradient HPLC with diode-array detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of iodine with water in pyridine-methanol medium. |
| Acid Value | Acid-Base Titration (NaOH) | Neutralization of acidic impurities with standardized sodium hydroxide solution using phenolphthalein indicator. |
| Organic Volatile Impurities | GC-FID | Detection and quantification of residual solvents using gas chromatography with flame ionization detection. |
Technical Specifications of 2'-Hydroxyacetophenone
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.5% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 39.0–41.0°C |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2'-Hydroxyacetophenone
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NMR Spectra of 2'-Hydroxyacetophenone
Packaging of 2'-Hydroxyacetophenone
Industrial 2'-Hydroxyacetophenone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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