5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1180132-17-5 |
| Product name | 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a pharmaceutical intermediate in the synthesis of kinase inhibitors (e.g., ALK and ROS1 inhibitors) | Introduced into target molecular structures via palladium-catalyzed coupling or nucleophilic substitution reactions, participating in multi-step organic synthesis routes |
| Chemical Research | Used as a building block for constructing heterocyclic compounds containing piperazine and pyridylamine motifs | Subjected to condensation, alkylation, or acylation reactions under inert atmosphere for high-throughput screening library construction |
Manufacturing Quality Control of 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine
| Test Item | Common Test Methods | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) Proton Nuclear Magnetic Resonance (¹H NMR) High-Performance Liquid Chromatography (HPLC) |
Confirm structure by characteristic IR absorption peaks, chemical shifts and coupling constants in ¹H NMR, or by matching retention time with reference standard under identical chromatographic conditions. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a mobile phase consisting of phosphate buffer and organic solvent (e.g., acetonitrile or methanol), and detect using a UV detector (typically around 254 nm). The assay is calculated by the external standard method. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Employ gradient elution to separate the main component from potential impurities (e.g., starting materials, intermediates, degradation products). Quantitation is performed using the area normalization method or the main component self-dilution method with correction factors. |
| Residual Solvents | Gas Chromatography (GC) | Headspace or direct injection is used with a polar capillary column such as DB-624 and an FID detector. Quantitative analysis of organic solvents (e.g., dichloromethane, methanol, ethanol, acetonitrile) employed during synthesis is conducted according to ICH Q3C guidelines. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant Temperature Atmospheric Drying | Dry the sample at a specified temperature (e.g., 105°C) to constant weight and determine the percentage loss in mass due to moisture or other volatile components. |
| Sulfated Ash (Residue on Ignition) | High-Temperature Ignition Method | Ignite the sample at high temperature (typically 700–800°C) to constant weight to determine the amount of inorganic residue, used to control residual inorganic salts or metal catalysts. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | After acid digestion of the sample, determine the levels of heavy metals such as lead, cadmium, mercury, and arsenic using AAS or ICP-MS, ensuring compliance with pharmacopoeial limits. |
| pH (if in solution) | pH Meter Method | Prepare an aqueous solution of specified concentration and measure its pH using a calibrated pH meter to assess whether acidity or alkalinity meets quality specifications. |
Technical Specifications of 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 142-146°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine
Safety Information of 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine
Industrial 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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