China Factory Direct
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| CAS number | 118156-93-7 |
| Product name | 1-BOC-3-PIPERIDINECARBOXALDEHYDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceuticals | Used as a synthetic drug intermediate for preparing biologically active piperidine derivatives (e.g., neurotransmitter receptor modulators, antidepressants, antipsychotics) | Applied in condensation, reduction, or cyclization reactions between 1-BOC-3-piperidinecarboxaldehyde and amines, aldehydes, or ketones to construct complex nitrogen-containing heterocycles |
| Chemical Synthesis | Used as a key building block in organic synthesis for constructing multifunctional molecules containing the piperidine ring | Applied as an electrophile in nucleophilic addition, reductive amination, Wittig reactions, or Mannich reactions to introduce dual functionality—aldehyde and BOC-protected amine groups |
| High-Throughput Screening | Used in constructing combinatorial chemistry libraries for screening potential drug lead compounds | Applied in solid-phase or solution-phase synthesis to rapidly generate structurally diverse piperidine derivative libraries via reactions with various amines or nucleophiles |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210-220 nm based on peak area comparison to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities using gradient HPLC-UV against qualified reference standards or threshold-based reporting. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., dichloromethane, methanol) by headspace GC with flame ionization detection using calibrated standards. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration where iodine reacts stoichiometrically with water in anhydrous pyridine/methanol medium. |
| Chiral Purity | Chiral HPLC-UV | Evaluates enantiomeric excess using chiral stationary phase HPLC with UV detection, comparing retention times and peak areas of enantiomers. |
| Heavy Metals | ICP-MS | Quantifies trace metals (e.g., Pb, Cd, Ni) after acid digestion by measuring elemental mass-to-charge ratios with high sensitivity and multi-element capability. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content by ignition at 600-750 C followed by precise weighing of residual non-volatile matter. |
| Acid Value | Acid-Base Titration | Determines free carboxylic acid or acidic impurities via titration with standardized NaOH solution using phenolphthalein indicator. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of sample against specified criteria (e.g., white to off-white crystalline powder, free-flowing). |
| Loss on Drying | Thermogravimetric Analysis (TGA) | Quantifies volatile content (excluding water) by measuring mass loss under controlled heating (e.g., 105 C, 2 h) in air or nitrogen. |
| Specific Optical Rotation | Polarimetry | Determines chiral compound concentration and enantiomeric identity by measuring angle of rotation of plane-polarized light in solution at specified wavelength and temperature. |
| Test Item | Specification |
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| Appearance | Colorless liquid |
| Purity | >=98.5% (LC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.