2-Hydroxymethyl-3-methyl-4-(3-methoxy propanoxyl)pyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 118175-10-3 |
| Product name | 2-Hydroxymethyl-3-methyl-4-(3-methoxy propanoxyl)pyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Hydroxymethyl-3-methyl-4-(3-methoxy propanoxyl)pyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Hydroxymethyl-3-methyl-4-(3-methoxy propanoxyl)pyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Hydroxymethyl-3-methyl-4-(3-methoxy propanoxyl)pyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of vitamin B6 (pyridoxine) and its derivatives | Organic synthesis for constructing the side-chain structure of the pyridine ring |
| Pharmaceutical Manufacturing | Preparation of biologically active pyridine-based compounds | Key intermediate in multi-step synthesis, participating in condensation, substitution, and related reactions |
| Chemical Research | Organic synthesis reagent or analytical standard | Synthesis and analytical research at laboratory scale |
Manufacturing Quality Control of 2-Hydroxymethyl-3-methyl-4-(3-methoxy propanoxyl)pyridine
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Assay (Main Component Content) | High-Performance Liquid Chromatography (HPLC) | A reversed-phase C18 column is used with water-acetonitrile or methanol as the mobile phase, employing gradient or isocratic elution. Detection is performed using a UV detector (typically at 254 nm or 280 nm). The content of the main component is calculated using external or internal standard methods, ensuring compliance with pharmacopoeia or corporate standards (e.g., ≥98.0%). |
| Related Substances (Impurity Profile) | HPLC Method (Impurity Detection) | The same or optimized HPLC method as used for assay is applied, with a reduced detection wavelength (e.g., 210 nm) to enhance impurity sensitivity. Impurity reporting thresholds (e.g., 0.1%) and identification thresholds (e.g., 0.5%) are established. Impurities are controlled through comparison with known impurity reference standards or by structural identification using LC-MS. |
| Water Content | Karl Fischer Titration | The Karl Fischer reagent composed of iodine, sulfur dioxide, pyridine, and methanol reacts quantitatively with water in the sample. Water content is determined by potentiometric or coulometric titration. This method is suitable for hygroscopic organic compounds such as hydrochloride salts, controlling water content ≤1.0% (depending on stability requirements). |
| Residual Solvents | Gas Chromatography (GC) | Headspace or direct injection GC-FID or GC-MS is used to detect common organic solvent residues (e.g., methanol, ethanol, acetone, acetonitrile, dichloromethane) according to ICH Q3C guidelines. Acceptable limits are set (e.g., acetonitrile ≤410 ppm). |
| Chloride Ion Content / Hydrochloride Confirmation | Ion Chromatography (IC) or Precipitation Titration | Chloride ion content is quantitatively determined by ion chromatography (suppressed conductivity detection), or chloride content is measured using silver nitrate titration. The hydrochloride equivalent is calculated based on molecular weight, confirming the stoichiometric ratio (e.g., theoretical Cl⁻ content ~16.5%). |
| Melting Point | Melting Point Apparatus | The melting point range is determined using the capillary method or an automatic melting point apparatus. It serves as a physical constant for identification, with a typical range of approximately 120–135°C (to be verified experimentally). |
| pH Value (Aqueous Solution) | pH Meter | The sample is prepared as an aqueous solution of specified concentration (e.g., 10 mg/mL), and the pH is measured using a calibrated pH meter. This reflects the acidic nature of the hydrochloride salt, typically ranging from pH 3.5–5.5. |
| Appearance and Color | Visual Inspection + Color Measurement | The sample is observed visually as a white to off-white crystalline powder. If necessary, a colorimeter (e.g., yellowness index) is used for quantitative color control to avoid contamination from oxidation or degradation products. |
| Heavy Metals | ICP-MS or Atomic Absorption Spectroscopy (AAS) | Lead, cadmium, mercury, and arsenic are tested according to pharmacopoeial general chapters (e.g., USP <231> or EP 2.5.10), with limits in ppm (e.g., ≤10 ppm), ensuring the safety of the active pharmaceutical ingredient. |
| Particle Size Distribution | Laser Diffraction or Microscopy | For APIs where solubility or formulation processing is critical, particle size parameters such as D50 are measured to ensure batch-to-batch consistency (e.g., D90 <50 μm). |
Technical Specifications of 2-Hydroxymethyl-3-methyl-4-(3-methoxy propanoxyl)pyridine
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142°C - 146°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Hydroxymethyl-3-methyl-4-(3-methoxy propanoxyl)pyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Hydroxymethyl-3-methyl-4-(3-methoxy propanoxyl)pyridine
Safety Information of 2-Hydroxymethyl-3-methyl-4-(3-methoxy propanoxyl)pyridine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-Hydroxymethyl-3-methyl-4-(3-methoxy propanoxyl)pyridine
Industrial 2-Hydroxymethyl-3-methyl-4-(3-methoxy propanoxyl)pyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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