tert-butyl 6-oxo-2-azaspiro[3.3]heptane-2-carboxylate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1181816-12-5 |
| Product name | tert-butyl 6-oxo-2-azaspiro[3.3]heptane-2-carboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for tert-butyl 6-oxo-2-azaspiro[3.3]heptane-2-carboxylate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk tert-butyl 6-oxo-2-azaspiro[3.3]heptane-2-carboxylate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of tert-butyl 6-oxo-2-azaspiro[3.3]heptane-2-carboxylate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Intermediate in the synthesis of antiviral drugs | Prepared via organic synthesis methods, such as nucleophilic substitution and cyclization reactions |
| Chemical Research | Organic synthesis intermediate for research on novel compounds | Prepared via multi-step organic synthesis |
| Biopharmaceuticals | Development of novel antibiotics or anti-infective agents | Pharmacological properties optimized through structural modification and biological activity testing |
Manufacturing Quality Control of tert-butyl 6-oxo-2-azaspiro[3.3]heptane-2-carboxylate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~210 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-UV | Separation and quantification of structurally related impurities using gradient HPLC/UPLC with UV detection; reported as area percent relative to main peak. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common solvents (e.g., THF, DMF, EtOAc, heptane) based on calibrated external standards. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Heavy Metals | ICP-MS | Quantitative multi-element analysis of toxic metals (e.g., Pb, Cd, Hg, Ni) after acid digestion, using isotopic detection with high sensitivity and low detection limits. |
| Optical Purity (Enantiomeric Excess) | Chiral HPLC-UV | Enantioseparation on a chiral stationary phase followed by UV detection; ee calculated from peak area ratio of enantiomers. |
| Residual Palladium | ICP-OES | Quantification of residual Pd catalyst after microwave-assisted nitric/hydrochloric acid digestion, using plasma emission at characteristic wavelengths. |
| Particle Size Distribution | Laser Diffraction | Measurement of dry or wet dispersed particle size via Mie scattering theory, reporting D10, D50, D90 values. |
| Loss on Drying (LOD) | Thermogravimetric Analysis (TGA) or Standard Oven Drying | Mass loss measured gravimetrically after controlled heating (e.g., 105 °C, 2 h) under specified atmospheric conditions. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | pH determined in a defined suspension (e.g., 10 mg/mL in water) using calibrated pH electrode, indicating acidic/basic impurity profile. |
| Residual Chloride | Ion Chromatography (IC) with Conductivity Detection | Separation and quantification of chloride ions after aqueous extraction, using anion-exchange column and suppressed conductivity detection. |
| Microbial Limits | Membrane Filtration + Culture Enumeration | Detection and enumeration of aerobic microorganisms and specified pathogens per pharmacopeial methods (e.g., USP <61>/<62>). |
Technical Specifications of tert-butyl 6-oxo-2-azaspiro[3.3]heptane-2-carboxylate
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.5% (GC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 82–86°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of tert-butyl 6-oxo-2-azaspiro[3.3]heptane-2-carboxylate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of tert-butyl 6-oxo-2-azaspiro[3.3]heptane-2-carboxylate
Safety Information of tert-butyl 6-oxo-2-azaspiro[3.3]heptane-2-carboxylate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of tert-butyl 6-oxo-2-azaspiro[3.3]heptane-2-carboxylate
Industrial tert-butyl 6-oxo-2-azaspiro[3.3]heptane-2-carboxylate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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