5-Chloroacetyl-6-chloro-1,3-dihydro-2H-indole-2-one Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 118307-04-3 |
| Product name | 5-Chloroacetyl-6-chloro-1,3-dihydro-2H-indole-2-one |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-Chloroacetyl-6-chloro-1,3-dihydro-2H-indole-2-one
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Chloroacetyl-6-chloro-1,3-dihydro-2H-indole-2-one Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Chloroacetyl-6-chloro-1,3-dihydro-2H-indole-2-one
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate for the synthesis of the anticoagulant drug rivaroxaban | Undergoes nucleophilic substitution with aqueous ammonia or amine reagents under basic conditions to construct the amide bond in the rivaroxaban molecule |
Manufacturing Quality Control of 5-Chloroacetyl-6-chloro-1,3-dihydro-2H-indole-2-one
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities based on relative retention times and response factors versus main peak. |
| Residual Solvents | GC-FID | Detection and quantification of volatile organic solvents using gas chromatography with flame ionization detection and external calibration. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) via inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Content | Potentiometric Titration | Determination of total chloride ions using silver nitrate titrant and silver indicator electrode. |
| Water Content | Karl Fischer Titration | Volumetric determination of water based on iodine-sulfur dioxide redox reaction in anhydrous methanol medium. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change under controlled heating rate. |
| Loss on Drying | Gravimetric Analysis | Mass loss measured after drying sample at specified temperature and time under vacuum or forced-air conditions. |
| Particle Size Distribution | Laser Diffraction | Sizing distribution analysis based on angular scattering pattern of laser light passing through dispersed particles. |
| pH of Aqueous Suspension | pH Meter | Measurement of hydrogen ion activity in a standardized suspension (e.g., 10% w/v in water) using calibrated pH electrode. |
| Specific Optical Rotation | Polarimetry | Determination of chiral purity by measuring rotation angle of plane-polarized light through a solution at specified concentration and path length. |
| Residue on Ignition | Gravimetric Ashing | Inorganic residue mass determined after high-temperature incineration to remove organic matter, followed by cooling and weighing. |
Technical Specifications of 5-Chloroacetyl-6-chloro-1,3-dihydro-2H-indole-2-one
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 162.0–166.0 °C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-Chloroacetyl-6-chloro-1,3-dihydro-2H-indole-2-one
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Safety Information of 5-Chloroacetyl-6-chloro-1,3-dihydro-2H-indole-2-one
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 5-Chloroacetyl-6-chloro-1,3-dihydro-2H-indole-2-one
Industrial 5-Chloroacetyl-6-chloro-1,3-dihydro-2H-indole-2-one Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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