Fmoc-D-Tyr(tBu)-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 118488-18-9 |
| Product name | Fmoc-D-Tyr(tBu)-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Fmoc-D-Tyr(tBu)-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Fmoc-D-Tyr(tBu)-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Fmoc-D-Tyr(tBu)-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Synthesis of peptide drugs | Serves as a key protected amino acid raw material in solid-phase peptide synthesis (SPPS) to construct peptide drug molecules containing D-tyrosine. |
| Pharmaceutical Industry | Drug research and screening | Used to synthesize D-peptide derivatives to enhance protease stability of peptide drugs, supporting new drug screening and development. |
| Biochemistry | Synthesis of biologically active peptides | Applied in synthesizing peptide fragments with defined biological activity to investigate the effects of D-amino acids on peptide conformation and bioactivity. |
| Scientific Research | Preparation of peptide reference standards | Employed for laboratory-scale synthesis of peptide reference standards or controls to support physicochemical property studies and analytical method development. |
Manufacturing Quality Control of Fmoc-D-Tyr(tBu)-OH
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 268 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC-UV; identification by retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DMF, THF, ethyl acetate) using gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration with iodine-based reagent, based on stoichiometric reaction with water. |
| Optical Purity (Enantiomeric Excess) | Chiral HPLC-UV | Separates D- and L-enantiomers on a chiral stationary phase and calculates enantiomeric excess from peak area ratio. |
| Heavy Metals | ICP-MS | Quantifies trace metal impurities (e.g., Pb, Cd, Ni, Cu) after acid digestion using inductively coupled plasma mass spectrometry. |
| Residual Palladium | ICP-MS | Specific quantification of palladium catalyst residues post-coupling synthesis using ICP-MS with isotope dilution or external calibration. |
| Chloride Content | Ion Chromatography | Measures chloride ion concentration via suppressed conductivity detection after anion exchange separation. |
| pH of Solution (1% w/v in water) | pH Meter | Determines acidity/basicity of aqueous suspension using calibrated pH electrode under standardized temperature and concentration conditions. |
| Loss on Drying | Gravimetric Analysis | Measures volatile content by weight loss after drying at 60 C under vacuum for 2 hours. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles by observation against white/black background under controlled lighting. |
Technical Specifications of Fmoc-D-Tyr(tBu)-OH
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +28.0 to +32.0 deg (c=1, in DMF) |
| Melting Point | 148 to 152 °C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Fmoc-D-Tyr(tBu)-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Fmoc-D-Tyr(tBu)-OH
Packaging of Fmoc-D-Tyr(tBu)-OH
Industrial Fmoc-D-Tyr(tBu)-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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