3-(Boc-amino)-5-trifluoromethyl-pyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1187055-61-3 |
| Product name | 3-(Boc-amino)-5-trifluoromethyl-pyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-(Boc-amino)-5-trifluoromethyl-pyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-(Boc-amino)-5-trifluoromethyl-pyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-(Boc-amino)-5-trifluoromethyl-pyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for antiviral drugs and protease inhibitors | Prepared via amino protection reaction of N-BOC-protected 3-amino-5-(trifluoromethyl)pyridine with isobutyryl chloride or di-tert-butyl dicarbonate |
| Pesticides | Intermediate for synthesizing novel insecticides or fungicides containing the 5-(trifluoromethyl)pyridine moiety | Starting from 3-(N-BOC-amino)-5-(trifluoromethyl)pyridine, followed by Boc deprotection and coupling with acyl chlorides or sulfonyl chlorides to construct the active molecule |
| Chemical Synthesis | Fluorinated heterocyclic building block for multistep organic synthesis | Serves as a key intermediate in palladium-catalyzed cross-coupling, nucleophilic substitution, or reductive amination reactions to construct complex molecular frameworks |
Manufacturing Quality Control of 3-(Boc-amino)-5-trifluoromethyl-pyridine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-MS | Separation and identification of impurities (e.g., de-Boc, hydrolyzed, or isomeric by-products) via retention time matching and/or mass spectral confirmation. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual solvents (e.g., THF, DMF, ethyl acetate) based on calibrated external standards. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with sample moisture. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pd, Ni, Fe) after acid digestion, using isotopic detection at sub-pptr sensitivity. |
| Residual Palladium | ICP-OES | Quantitative analysis of palladium catalyst residue post-digestion using plasma excitation and element-specific emission wavelengths. |
| Optical Rotation | [α]D Measurement | Determination of specific optical rotation using a polarimeter at 589 nm (Na D-line) to confirm chiral integrity (if applicable to synthesis route). |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution via Mie scattering theory using dispersed aerosolized sample. |
| Loss on Drying (LOD) | Thermogravimetric Analysis (TGA) | Measurement of mass loss upon controlled heating (e.g., 105°C, 2 h) to assess volatile content and residual solvents/moisture. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) to detect acidic/basic degradation products or residual reagents. |
| N-BOC Group Content | 1H NMR Spectroscopy | Quantitative assessment of BOC protecting group integrity and stoichiometry via integration of tert-butyl singlet (~1.4 ppm) relative to aromatic protons. |
| Melting Point | Automated Melting Point Apparatus | Determination of solid-state phase transition temperature range using calibrated capillary method per USP <741>. |
Technical Specifications of 3-(Boc-amino)-5-trifluoromethyl-pyridine
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128°C - 132°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-(Boc-amino)-5-trifluoromethyl-pyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-(Boc-amino)-5-trifluoromethyl-pyridine
Safety Information of 3-(Boc-amino)-5-trifluoromethyl-pyridine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3-(Boc-amino)-5-trifluoromethyl-pyridine
Industrial 3-(Boc-amino)-5-trifluoromethyl-pyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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