IMidazo[1,2-a]pyridine-2-carboxylic acid, 7-broMo-, ethyl ester Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1187236-18-5 |
| Product name | IMidazo[1,2-a]pyridine-2-carboxylic acid, 7-broMo-, ethyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1187236-18-5
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1187236-18-5 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1187236-18-5
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Organic synthesis intermediate | Used to synthesize biologically active imidazopyridine compounds as key precursors in drug molecule construction |
| Fine chemicals | Active pharmaceutical ingredient (API) synthesis | Participates in structural modification during transition metal-catalyzed coupling reactions to prepare candidate compounds for anticancer, antiviral, or central nervous system therapies |
| Biopharmaceuticals | Kinase inhibitor development | Serves as a core scaffold in kinase-targeted drug development processes, supporting structural optimization and structure–activity relationship (SAR) studies |
Manufacturing Quality Control of 1187236-18-5
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual solvents (e.g., ethanol, DMF, dichloromethane) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, using isotopic detection with high sensitivity and low detection limits. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in solution after sample dissolution and dilution. |
| Sulfate Impurity | Ion Chromatography | Separation and conductivity detection of sulfate ions following sample preparation and filtration. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after controlled ashing at 700-800 C and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of bulk material under controlled white light against defined specifications. |
| Bulk Density | USP <616> Tap Density Method | Measurement of mass per unit volume after standardized tapping to assess flow and handling properties. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution by measuring angular variation in laser light scattering from dispersed particles in air or liquid medium. |
Technical Specifications of 1187236-18-5
| Test Item | Specification |
|---|---|
| Appearance | Off-White to Light Yellow Solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1187236-18-5
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1187236-18-5
Packaging of 1187236-18-5
Industrial 1187236-18-5 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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