China Factory Direct
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| CAS number | 1187931-23-2 |
| Product name | (R)-2-AMINOMETHYL-1-N-CBZ-PYRROLIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceuticals | Pharmaceutical intermediates | Used in the synthesis of chiral drug molecules, particularly as a key intermediate in the production of antidepressants and neuroactive agents |
| Chemical Synthesis | Chiral catalyst or ligand precursor | Serves as a precursor to chiral catalysts or ligands in asymmetric synthesis, enabling catalytic reaction construction |
| Research & Development | Organic synthesis research | Applied in methodology development for novel organic reactions, including C–H bond activation and amination reactions |
| Pharmaceutical Manufacturing | Active pharmaceutical ingredient (API) synthesis | Employed as a chiral building block for constructing complex molecular frameworks during final drug molecule synthesis |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Enantiomeric Excess (ee) | Chiral HPLC | Separation of (R)- and (S)-enantiomers on a chiral stationary phase, with UV detection and calculation of ee from peak area ratio. |
| Residual Solvents | GC-FID | Identification and quantification of common organic solvents using gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration with iodine-based reagent; water reacts stoichiometrically to determine trace moisture content. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion and plasma ionization. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with suppressed conductivity detection. |
| Sulfate Impurity | IC or Turbidimetry | Quantification of sulfate via ion chromatography or by measuring turbidity formed with barium chloride in acidic medium. |
| Residual Palladium | ICP-OES | Elemental determination of palladium catalyst residues after microwave-assisted acid digestion and plasma optical emission detection. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of solid or solution against defined specifications under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating purity and identity. |
| Particle Size Distribution | Laser Diffraction | Measurement of particle size distribution in dry or wet dispersion based on angular dependence of scattered laser light. |
| Microbial Contamination | Membrane Filtration / TSA Plate Count | Enumeration of aerobic microorganisms after filtration and incubation on tryptic soy agar plates per pharmacopeial methods. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128–132°C |
| Optical Rotation | +15.0 to +17.0° (c=1, in methanol) |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.