China Factory Direct
|
|
| CAS number | 1187932-13-3 |
| Product name | tert-butyl 3-(methylamino)pyrrolidine-1-carboxylate;hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Used as a pharmaceutical intermediate in the synthesis of antitumor agents and central nervous system (CNS) drugs | Serves as a key starting material in multistep syntheses—following Boc protection of 3-(methylamino)pyrrolidine hydrochloride—and participates in acylation, coupling, and other reactions to construct the target molecular framework |
| Organic Synthesis | Used as a nitrogen-containing heterocyclic building block in fine chemical synthesis | Acts as a nitrogen-containing heterocyclic precursor in catalytic hydrogenation, nucleophilic substitution, or condensation reactions to enable functionalization |
| Biochemical Research | Used for structural modification of probe molecules or bioactive compounds | Derivatized via its side-chain amino group to prepare fluorescent labels or bioactive probes for target identification and mechanism-of-action studies |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210-230 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC with UV detection and relative response factors. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, ethyl acetate, toluene) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration using iodine-based redox reaction in anhydrous methanol medium. |
| Chloride Impurity | Ion Chromatography | Quantifies chloride ions using suppressed conductivity detection after separation on anion-exchange column. |
| Heavy Metals | ICP-MS | Detects trace metal impurities (e.g., Pb, Cd, Ni, Cu) by inductively coupled plasma mass spectrometry with isotopic detection. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content by high-temperature incineration followed by weighing of residual non-volatile matter. |
| Optical Rotation | Polarimetry | Determines specific optical rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measures hydrogen ion activity in a defined aqueous suspension or solution using calibrated glass electrode. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or wet dispersed sample to determine volume-based particle size distribution via light scattering pattern analysis. |
| Bulk Density | USP <616> Tapped Density Method | Determines mass per unit volume by measuring volume before and after standardized mechanical tapping of powder in a graduated cylinder. |
| Microbial Contamination | Membrane Filtration and Plate Count | Detects aerobic microorganisms by filtration, membrane transfer to culture media, and colony enumeration after incubation. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142-146°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -15.0 to -19.0° (c=1, in methanol) |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.