(2R,3R)-rel-1,3-Piperidinedicarboxylic acid, 2-methyl-, 1-(phenylmethyl) ester Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1187933-24-9 |
| Product name | (2R,3R)-rel-1,3-Piperidinedicarboxylic acid, 2-methyl-, 1-(phenylmethyl) ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1187933-24-9
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1187933-24-9 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1187933-24-9
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral intermediate for synthesizing protease inhibitors or neuroactive drugs | Stereoselective esterification of (2R,3R)-rel-1,3-piperidinedicarboxylic acid with benzyl alcohol, using a coupling reagent such as DCC or EDC |
Manufacturing Quality Control of 1187933-24-9
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~210 nm, comparing peak area against a certified reference standard. |
| Chiral Purity | (R,R)-Diastereomeric Excess | Chiral HPLC |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection, using internal standard calibration for common solvents (e.g., MeOH, EtOAc, toluene). |
| Heavy Metals | ICP-MS | Quantitative multi-element analysis after acid digestion; detects metals (e.g., Pb, Cd, Ni, Pd) at sub-ppb levels based on elemental mass spectrometry. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with sample moisture. |
| Appearance and Color | Visual Inspection & APHA Color Scale | Subjective visual assessment against water-white standard; color quantified by APHA (Pt-Co) scale using spectrophotometric comparison. |
| Residual Palladium | ICP-OES | After microwave-assisted nitric/hydrochloric acid digestion, Pd quantified by atomic emission at characteristic wavelength (e.g., 340.458 nm). |
| Related Substances | HPLC-UV (Forced Degradation Study) | Gradient HPLC-UV method validated for separation and quantification of process-related impurities and degradation products (e.g., hydrolysis, oxidation). |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measured by controlled heating; onset and range indicate crystallinity and purity per USP <741>. |
| Residual Benzyl Chloride | GC-MS | Headspace or direct injection GC-MS with selected ion monitoring (SIM) for benzyl chloride (m/z 91, 108) using isotopic internal standard. |
| Optical Rotation | Polarimetry | Measurement of specific rotation ([α]D) at 20 °C using sodium D-line (589 nm) to confirm chiral integrity and batch consistency. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion via light scattering to determine D10, D50, D90 per ISO 13320. |
| Microbial Limits | Membrane Filtration + TSA/TSA+CA | Enumeration of aerobic microorganisms and absence of specified pathogens (e.g., E. coli, S. aureus) per USP <61> and <62>. |
Technical Specifications of 1187933-24-9
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Optical Rotation | [α]D²⁰ = +12.5° to +14.5° (c = 1.0 in methanol) |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1187933-24-9
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of 1187933-24-9
Industrial 1187933-24-9 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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