2-(Trifluoromethoxy)-4-bromobenzonitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1187983-97-6 |
| Product name | 2-(Trifluoromethoxy)-4-bromobenzonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-(Trifluoromethoxy)-4-bromobenzonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-(Trifluoromethoxy)-4-bromobenzonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-(Trifluoromethoxy)-4-bromobenzonitrile
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediate | Serves as an aromatic building block; the bromo group enables coupling reactions (e.g., Suzuki coupling), while the nitrile group undergoes functional transformations to construct drug molecule scaffolds containing a trifluoroethoxy moiety. |
| Agrochemicals | Agrochemical Intermediate | Used in synthesizing novel fluorinated agrochemicals (e.g., insecticides or herbicides); trifluoroethoxy groups are introduced via functional group modification to enhance bioactivity and metabolic stability. |
| Advanced Materials | OLED and Organic Optoelectronic Material Synthesis | Serves as a precursor for electron-transport or hole-blocking layer materials; the strongly electron-withdrawing trifluoroethoxy and nitrile groups jointly optimize the material’s energy-level structure. |
| Organic Synthesis | Starting Material | Functions as a multifunctional substrate in complex organic compound synthesis; the nitrile group can be hydrolyzed to a carboxylic acid or reduced to an amine, and the bromo site enables carbon–carbon bond formation. |
Manufacturing Quality Control of 2-(Trifluoromethoxy)-4-bromobenzonitrile
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at ~220 nm, comparing peak area to a certified reference standard. |
| Related Substances (Impurities) | HPLC-UV or UPLC-MS | Separation and detection of structurally related impurities (e.g., des-bromo, hydrolysis, or oxidation by-products) via chromatographic resolution and spectral identification/quantification. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify residual solvents (e.g., DMF, toluene, methanol) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration quantifying water based on the stoichiometric reaction of iodine with water in anhydrous pyridine/methanol medium. |
| Inorganic Residues (Sulfated Ash) | Gravimetric Analysis | High-temperature incineration followed by sulfuric acid treatment and weighing of non-volatile residue. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using mass spectrometry for ultra-trace detection. |
| Residual Catalyst (Pd, Ni, Cu) | ICP-OES | Quantification of transition metal catalysts post-digestion via atomic emission spectroscopy at element-specific wavelengths. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition temperature using calibrated capillary apparatus per USP <741>. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using Mie scattering theory to derive D10, D50, D90 values. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and conductivity detection of chloride ions after sample dissolution and filtration. |
| Residual Bromine (as Br⁻) | Potentiometric Titration with AgNO₃ | Titration with silver nitrate using silver indicator electrode; endpoint detected by potential inflection due to AgBr precipitation. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to assess chiral purity (if applicable; compound is achiral but method included for stereochemical verification). |
Technical Specifications of 2-(Trifluoromethoxy)-4-bromobenzonitrile
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.5% (GC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 78–82°C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-(Trifluoromethoxy)-4-bromobenzonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-(Trifluoromethoxy)-4-bromobenzonitrile
Safety Information of 2-(Trifluoromethoxy)-4-bromobenzonitrile
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-(Trifluoromethoxy)-4-bromobenzonitrile
Industrial 2-(Trifluoromethoxy)-4-bromobenzonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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