N-Acetyl-L-leucine Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 1188-21-2 |
| Product name | N-Acetyl-L-leucine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for N-Acetyl-L-leucine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-Acetyl-L-leucine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-Acetyl-L-leucine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of antibiotic drugs | Prepared via reaction of L-leucine with acetyl chloride |
| Food Additives | Intermediate in flavor and fragrance synthesis | Used as an amino acid derivative in flavoring agent synthesis |
| Cosmetics | Amino acid component in skincare products | Applied in moisturizing and skin-repair formulations |
| Biobiochemistry | Research reagent for peptide and protein synthesis | Employed as an amino acid monomer in solid-phase peptide synthesis |
| Pesticides | Intermediate in insecticide and herbicide synthesis | Used for structural modification in organic synthesis pathways |
Manufacturing Quality Control of N-Acetyl-L-leucine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Acid-Base Titration | Quantifies N-acetyl-L-leucine by titration with standardized NaOH using phenolphthalein indicator; based on neutralization of carboxylic acid group. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light by chiral N-acetyl-L-leucine in solution; confirms enantiomeric identity and purity. |
| Loss on Drying | Gravimetric (Thermogravimetric) | Determines volatile content including water and solvents by weight loss after drying at 105 C for 2 hours. |
| Residue on Ignition | Gravimetric (Sulfated Ash) | Measures non-volatile inorganic impurities by ashing at 600 C and weighing residual sulfate ash. |
| Heavy Metals (as Pb) | Colorimetric (Thioacetamide Method) | Forms colored metal-sulfide complexes in acidic medium; compared visually or spectrophotometrically against lead standard. |
| Chloride | Argentometric Titration (Mohr Method) | Titration with standardized AgNO3 using K2CrO4 indicator; forms red Ag2CrO4 endpoint after complete AgCl precipitation. |
| Sulfate | Barium Sulfate Gravimetry | Precipitates sulfate as BaSO4 in acidic medium, filters, dries, and weighs to quantify sulfate impurity. |
| Related Substances | HPLC (UV Detection) | Separates and quantifies structurally related impurities (e.g., L-leucine, N-acetyl-D-leucine) using reversed-phase C18 column and UV detection at 210 nm. |
| Water Content | Karl Fischer Titration | Electrochemically determines water via iodine-sulfur dioxide reaction in methanol-based reagent; stoichiometric and specific. |
| pH (1% aqueous solution) | Potentiometric (pH Meter) | Measures hydrogen ion activity in aqueous solution using calibrated glass electrode and reference electrode. |
| Microbial Contamination | Membrane Filtration | Filters sample through sterile membrane, incubates on appropriate agar media, and enumerates viable aerobic bacteria and molds/yeasts. |
| Residual Solvents (e.g., Ethanol, Acetone) | GC-FID | Separates and quantifies volatile organic solvents using gas chromatography with flame ionization detection and external calibration. |
Technical Specifications of N-Acetyl-L-leucine
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 124–128°C |
| Optical Rotation | −23±3° (c=1, in 1M HCl) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of N-Acetyl-L-leucine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-Acetyl-L-leucine
Packaging of N-Acetyl-L-leucine
Industrial N-Acetyl-L-leucine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply