N-Acetyl-L-glutamic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1188-37-0 |
| Product name | N-Acetyl-L-glutamic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-Acetyl-L-glutamic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-Acetyl-L-glutamic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-Acetyl-L-glutamic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Targeted therapy for urea cycle disorders (e.g., N-acetylglutamate synthase deficiency), supplementing endogenous N-acetyl-L-glutamate to activate carbamoyl phosphate synthetase I (CPSI) | Administered intravenously as an enzyme activator in the mitochondrial urea cycle initiation step |
| Pharmaceuticals | Component of amino acid infusions and parenteral nutrition formulations, supporting nitrogen balance and hepatic function | Formulated aseptically with essential and non-essential amino acids for clinical parenteral nutrition support |
| Food | Nutritional fortificant (approved in specific jurisdictions), used in infant formula and foods for special medical purposes to supply a conditionally essential amino acid precursor | Added within limits specified by standards such as GB 14880–2012, followed by homogenization via spray drying or wet-mixing processes |
| Biotechnology | Cell culture additive that enhances growth and recombinant protein expression stability in mammalian cells (e.g., CHO cells) | Supplemented into basal media (e.g., DMEM/F12) at typical concentrations of 0.1–1.0 mM to cooperatively modulate glutamine metabolism pathways |
Manufacturing Quality Control of N-Acetyl-L-glutamic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Acid-Base Titration | Quantifies N-acetyl-L-glutamic acid content by titration with standardized NaOH using phenolphthalein indicator. |
| Loss on Drying | Gravimetric Analysis | Measures weight loss after drying at 105 C for 2 hours to determine volatile content and moisture. |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content by incineration at 600 C followed by weighing of residual ash. |
| Specific Optical Rotation | Polarimetry | Measures optical activity using sodium D-line light to confirm chiral purity and identity. |
| Heavy Metals (as Pb) | Colorimetric Sulfide Precipitation | Compares sample solution color intensity after sulfide reaction with lead standard solutions. |
| Chloride | Argentometric Titration | Quantifies chloride ions by titration with silver nitrate using potassium chromate indicator. |
| Sulfate | Barium Sulfate Gravimetry | Precipitates sulfate as BaSO4 and determines mass after filtration and drying. |
| Related Substances | HPLC with UV Detection | Separates and quantifies impurities using reversed-phase HPLC and UV absorbance at 210 nm. |
| Water Content | Karl Fischer Titration | Measures trace water via coulometric or volumetric titration with iodine-based reagent. |
| pH of Aqueous Solution | Potentiometric Measurement | Determines hydrogen ion activity using calibrated pH electrode in 1% w/v aqueous solution. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic microorganisms and detects specified pathogens per USP <61> and <62>. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of dry powder using light scattering principles and Mie theory. |
Technical Specifications of N-Acetyl-L-glutamic acid
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=99.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 187-191°C |
| Optical Rotation | -13.0 to -17.0° (c=1, in 1M HCl) |
| Total Impurities | <=1.0% (HPLC) |
| Single Impurity | <=0.3% (HPLC) |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-Acetyl-L-glutamic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-Acetyl-L-glutamic acid
Packaging of N-Acetyl-L-glutamic acid
Industrial N-Acetyl-L-glutamic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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