China Factory Direct
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| CAS number | 118864-75-8 |
| Product name | (1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates for certain antidepressant and antipsychotic drugs | Prepared via organic synthesis methods, such as reduction or cyclization reactions |
| Chemicals | Organic synthesis intermediate for producing other nitrogen-containing heterocyclic compounds | Further functionalized from phenyl-substituted tetrahydroisoquinoline structures |
| Research | Chemical research and analysis, used as a reference standard or certified reference material | Obtained through chemical synthesis or natural extraction |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 220-280 nm based on peak area comparison to reference standard. |
| Enantiomeric Excess (ee) | Chiral HPLC | Measures enantiomeric purity by separation on a chiral stationary phase and UV detection, calculating ee from peak area ratio of (S)- and (R)-enantiomers. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., methanol, toluene) using gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration with iodine generated electrochemically or added stoichiometrically in pyridine-methanol solvent. |
| Heavy Metals | ICP-OES | Quantifies elements such as Pb, Cd, Hg, and Ni after acid digestion by measuring atomic emission intensities at characteristic wavelengths. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and suppressed conductivity detection. |
| Related Substances | HPLC-UV | Identifies and quantifies structurally related impurities (e.g., starting materials, intermediates, degradants) via gradient HPLC with UV detection. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using controlled heating and visual observation of phase change. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation at 589 nm using sodium D-line light source and polarimeter to confirm chiral integrity and concentration. |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content by ignition at 700-800 C followed by weighing of residual residue. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a standardized suspension (e.g., 1% w/v in water) using calibrated glass electrode. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution of solid particles in suspension using angular scattering pattern of laser beam. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Optical Rotation | +10.0 to +14.0 (c=1, in methanol) |
| Melting Point | 128 to 132 °C |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.