China Factory Direct
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| CAS number | 118904-37-3 |
| Product name | FMOC-D-ALLO-ILE-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of peptide-based drugs; serves as a protecting group for D-alloisoleucine | Introduced as an N-(9-fluorenylmethoxycarbonyl) (Fmoc) protecting group onto D-alloisoleucine in solid-phase or solution-phase peptide synthesis |
| Biochemistry | Synthesis of structurally defined peptides and protein fragments | Stepwise solid-phase peptide synthesis using the Fmoc strategy |
| Polymeric Materials | Preparation of functional peptide-based materials | Incorporation of specific amino acid structures via controlled polymerization and crosslinking techniques |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at ~265 nm, based on peak area comparison against certified reference standard. |
| Enantiomeric Purity | Chiral HPLC | Resolves D- and L-enantiomers on a chiral stationary phase; enantiomeric excess calculated from peak area ratio. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents (e.g., DMF, DCM, MeOH) using gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration with iodine-based reagent, based on stoichiometric electrochemical reaction. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni, Pd) after acid digestion using inductively coupled plasma mass spectrometry for sub-ppq sensitivity. |
| Residual Palladium | ICP-OES | Measures palladium residue (from coupling catalysts) after microwave-assisted acid digestion using inductively coupled plasma optical emission spectroscopy. |
| Appearance and Color | Visual Inspection & APHA Color Scale | Assesses physical state (white to off-white crystalline powder) and color intensity by comparison to APHA standard solutions under controlled lighting. |
| Loss on Drying (LOD) | Gravimetric Thermogravimetry | Measures weight loss upon heating at 105 °C under vacuum or nitrogen, reflecting volatile content including residual solvents and moisture. |
| Related Substances | HPLC-UV (Forced Degradation Study) | Identifies and quantifies structurally related impurities (e.g., deprotected amine, dipeptide, oxidation products) using stability-indicating HPLC method. |
| pH of Solution (1% w/v in Water) | Potentiometric pH Measurement | Determines acidity/basicity of aqueous suspension using calibrated pH electrode; reflects residual acidic/basic reagents or degradation. |
| Specific Optical Rotation | [α]D | Measures chiral optical activity at 589 nm using sodium D-line polarimeter; confirms identity and enantiomeric integrity. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or wet dispersed sample to determine D10, D50, D90 values; impacts filtration, dissolution, and handling performance. |
| Microbial Limits | Membrane Filtration + Culture | Detects aerobic microorganisms and absence of specified pathogens (e.g., E. coli, S. aureus) per Ph. Eur./USP <61> and <62>. |
| Test Item | Specification |
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| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -13.5 to -11.5 deg (c=1, DMF) |
| Melting Point | 124 to 128 °C |
| Identification (NMR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.