1-METHYL-4-PIPERIDONE-2,2,6,6-D4 Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1189723-14-5 |
| Product name | 1-METHYL-4-PIPERIDONE-2,2,6,6-D4 |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-METHYL-4-PIPERIDONE-2,2,6,6-D4
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-METHYL-4-PIPERIDONE-2,2,6,6-D4 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-METHYL-4-PIPERIDONE-2,2,6,6-D4
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Isotopically labeled intermediates for synthesizing deuterated drug molecules (e.g., deuterated piperidine derivatives) to study metabolic stability, pharmacokinetics, and mechanism of action | Used as a key deuterated building block in organic synthesis reactions such as reductive amination, N-alkylation, and cycloaddition; commonly applied to construct candidate drug molecules containing a deuterated piperidine ring |
| Analytical Testing | Internal standard for quantitative LC-MS analysis of drugs and their metabolites containing the 1-methyl-4-piperidone structure | Coinjected with the sample at a known concentration; enables highly selective and precise isotope dilution quantification by monitoring characteristic ion pairs (e.g., m/z differences) |
Manufacturing Quality Control of 1-METHYL-4-PIPERIDONE-2,2,6,6-D4
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | GC-FID or GC-MS | Quantitative determination using gas chromatography with flame ionization detection or mass spectrometric detection, relative to a certified reference standard. |
| Deuterium Isotopic Purity | 1H NMR Spectroscopy | Measurement of residual proton signal intensity at characteristic positions (e.g., C3-H, C5-H) to confirm deuterium incorporation at 2,2,6,6-positions. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration based on the stoichiometric reaction of iodine with water in a pyridine-methanol solvent system. |
| Residual Solvents | GC-FID | Separation and quantification of common organic solvents (e.g., acetone, methanol, DCM) using headspace or direct injection GC. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of toxic elements (e.g., Pb, Cd, Hg, As) after acid digestion and dilution. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride anions in aqueous solution after sample dissolution and filtration. |
| Acid Value | Acid-Base Titration | Neutralization of acidic impurities with standardized sodium hydroxide solution using phenolphthalein indicator. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated digital melting point instrument. |
| Residue on Ignition | Gravimetric Analysis | Weighing of non-volatile residue remaining after high-temperature ashing of sample in a platinum crucible. |
| Related Substances | HPLC-UV | Separation and UV detection of structurally related impurities using reversed-phase C18 column and gradient elution. |
| Microbial Contamination | Membrane Filtration | Quantitative recovery and enumeration of aerobic microorganisms from filtered sample solution onto nutrient agar plates. |
Technical Specifications of 1-METHYL-4-PIPERIDONE-2,2,6,6-D4
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Conforms to reference standard |
| Odor | Characteristic piperidone-like odor |
| Refractive Index (n20/D) | 1.475–1.485 |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-METHYL-4-PIPERIDONE-2,2,6,6-D4
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Safety Information of 1-METHYL-4-PIPERIDONE-2,2,6,6-D4
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1-METHYL-4-PIPERIDONE-2,2,6,6-D4
Industrial 1-METHYL-4-PIPERIDONE-2,2,6,6-D4 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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