Methyl salicylate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 119-36-8 |
| Product name | Methyl salicylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent GradeFood GradeCosmetic Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Methyl salicylate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Methyl salicylate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Methyl salicylate
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Active ingredient in topical analgesic and anti-inflammatory preparations for relieving muscle pain, arthritis, and sprains | Formulated into topical dosage forms such as ointments, creams, and transdermal patches |
| Fine Fragrances & Cosmetics | Fragrance raw material imparting wintergreen oil aroma | Incorporated into consumer products including perfumes, soaps, shampoos, and toothpastes |
| Food | Food flavoring agent (used within specified limits) for confectionery and chewing gum | Added as a synthetic food flavoring in compliance with regulatory standards such as GB 2760 |
| Agriculture | Plant growth regulator and elicitor of disease resistance signaling | Applied via foliar spray or soil treatment to activate systemic acquired resistance (SAR) in plants |
| Chemical Industry | Organic synthesis intermediate | Used in the synthesis of other salicylic acid derivatives or pharmaceutical intermediates |
| Analytical Chemistry | Reference standard or internal standard in chromatographic analysis | Prepared as standard solutions for gas chromatography (GC) or high-performance liquid chromatography (HPLC) analysis |
Manufacturing Quality Control of Methyl salicylate
| Test Item | Common Test Methods | Method Overview |
|---|---|---|
| Appearance and Physical Characteristics | Visual inspection, physical property testing | Observe the sample as a colorless to pale yellow clear liquid with a characteristic wintergreen odor; measure physical constants such as refractive index and density, ensuring they fall within pharmacopoeial specifications (e.g., refractive index 1.540–1.544). |
| Identification | Infrared Spectroscopy (IR) | Determine characteristic absorption peaks using an infrared spectrometer and compare with reference spectra to confirm functional groups such as ester (C=O at 1730 cm⁻¹), phenolic hydroxyl (O-H at 3200 cm⁻¹), and benzene ring structures. |
| Identification | Thin-Layer Chromatography (TLC) | Use silica gel G plates with ethyl acetate-petroleum ether (1:1) as the mobile phase, and ferric chloride solution as the developing reagent. After hydrolysis of methyl salicylate to salicylic acid, a purple spot forms upon reaction with FeCl₃, matching the Rf value of the reference standard. |
| Assay | Gas Chromatography (GC) | Use a capillary column (e.g., DB-5) with FID detection, applying internal or external standard method for quantification. Common internal standards include n-tetradecane or diethyl phthalate. Calculate methyl salicylate content based on peak area, typically requiring ≥98.0%. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Employ a C18 reversed-phase column with methanol-water (70:30) as the mobile phase and UV detection at λ=275 nm. Quantify using external standard method, suitable for accurate determination of thermally unstable or less volatile samples. |
| Water Content | Karl Fischer Titration (KF) | Quantitatively react Karl Fischer reagent with water in the sample and determine trace moisture by potentiometric or coulometric titration. Limit water content to ≤0.5% to prevent hydrolytic degradation. |
| Impurity Testing | Gas Chromatography (GC) | Detect potential impurities such as salicylic acid, methanol, and phenol using programmed temperature ramping. Compare impurity peak areas to the main peak; limit individual impurities to ≤0.1% and total impurities to ≤0.5%. |
| Impurity Testing | High-Performance Liquid Chromatography (HPLC) | Detect hydrolysis products like salicylic acid and other polar impurities. Offers high sensitivity and accurate quantification of low-concentration impurities, compliant with ICH Q3B guidelines. |
| Acid Value / Free Acid | Acid-Base Titration | Titrate free salicylic acid in the sample with standardized sodium hydroxide solution using phenolphthalein as indicator. Calculate acid value (mg KOH/g), limiting it to ≤0.5 to ensure purity. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After ashing or acid digestion of the sample, determine levels of heavy metals such as lead, arsenic, cadmium, and mercury. Must comply with pharmacopoeial limits (e.g., lead ≤5 ppm). |
| Residual Solvents | Gas Chromatography (GC) | Test for residual solvents such as methanol, ethanol, and acetone according to ICH Q3C guidelines. Use headspace sampling and internal standard method to ensure compliance with permitted exposure limits. |
Technical Specifications of Methyl salicylate
| Test Item | Specification |
|---|---|
| Appearance | Colorless to light yellow clear liquid |
| Purity | >=98.5% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.534–1.538 |
| Relative Density (20°C/25°C) | 1.172–1.178 g/cm³ |
| Odor | Characteristic wintergreen odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Methyl salicylate
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NMR Spectra of Methyl salicylate
Packaging of Methyl salicylate
Industrial Methyl salicylate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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