China Factory Direct
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| CAS number | 119-91-5 |
| Product name | 2,2'-Biquinoline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Organic Synthesis | Ligand for transition-metal-catalyzed reactions | Used as chiral or achiral bidentate nitrogen ligands to form complexes with metals such as palladium, copper, and nickel; applied in cross-coupling reactions including Suzuki coupling, Heck reaction, and C–N coupling |
| Materials Science | Electron-transport material for organic light-emitting diodes (OLEDs) | Applied as an electron-transport layer (ETL) in vacuum thermal evaporation or solution-processing film formation to enhance device electron mobility and electroluminescent efficiency |
| Analytical Chemistry | Fluorescent probe and colorimetric reagent for metal ion detection | Forms complexes with metal ions such as Cu²⁺, Zn²⁺, and Fe³⁺ in aqueous or mixed solvents, resulting in characteristic fluorescence enhancement or absorption spectral shifts for quantitative analysis |
| Pharmaceutical R&D | Drug intermediate and scaffold for metalloproteinase inhibitors | Integrated into quinoline-based antitumor and antibacterial lead compounds via multistep organic synthesis—including nitration, reduction, acylation, and coupling—to construct target molecules |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies 2,2'-biquinoline content by separation on a reversed-phase column and UV absorbance detection at ~254 nm. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., monoquinoline, triquinoline, isomers) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Identifies and quantifies volatile organic solvents (e.g., ethanol, toluene, DMF) by gas chromatography with flame ionization detection. |
| Moisture Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration using iodine-based reagent stoichiometry. |
| Heavy Metals | ICP-OES | Measures total elemental impurities (Pb, Cd, Hg, As, etc.) after acid digestion by optical emission spectroscopy. |
| Chloride Content | Ion Chromatography | Quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after high-temperature combustion in presence of sulfuric acid, followed by weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against standard references. |
| Solubility | Qualitative Dissolution Test | Evaluates complete dissolution in specified solvents (e.g., ethanol, chloroform) within defined time and temperature. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a standardized suspension (e.g., 1% w/v in water) using calibrated electrode. |
| Bulk Density | Tap Density Tester | Determines mass per unit volume after standardized tapping; indicates flowability and packing behavior. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.5% (by LC-MS) |
| Melting Point | 102–106°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.